SCHEMBL4260911

SCHEMBL4260911

CC(=O)SCc1ccc(C#Cc2ccc(-c3c4nc(c(-c5c(C)cc(C)cc5C)c5ccc([nH]5)c(-c5c(C)cc(C)cc5C)c5nc(c(-c6c(C)cc(C)cc6C)c6ccc3[nH]6)C=C5)C=C4)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 4/20 0.41
▸ CYCS P99999 4/20 0.41
▸ ABCG2 Q9UNQ0 1/20 0.41
▸ ENPP2 Q13822 1/20 0.38
▸ TERT O14746 4/20 0.35
▸ FFAR1 O14842 2/20 0.32
▸ KDM4E B2RXH2 1/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ CYP1A2 P05177 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ HPGD P15428 1/20 0.31
▸ CYP2C19 P33261 1/20 0.31
▸ RECQL P46063 1/20 0.31
▸ KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4263830 0.94 TOP1 (0.46) TOP1CYCSABCG2ENPP2TERT
SCHEMBL4266706 0.85 TOP1 (0.44) TOP1CYCSABCG2ENPP2TERT
SCHEMBL4264116 0.84 TOP1 (0.44) TOP1CYCSABCG2ENPP2TERT
SCHEMBL4258798 0.82 TOP1 (0.43) TOP1CYCSABCG2ENPP2TERT
SCHEMBL4259964 0.78 TOP1 (0.49) TOP1CYCSABCG2ENPP2TERT
SCHEMBL79553 0.78 TOP1 (0.47) TOP1CYCSABCG2ENPP2TERT
SCHEMBL5064811 0.77 TERT (0.42) TOP1CYCSABCG2ENPP2TERT
SCHEMBL4267270 0.77 TOP1 (0.33) TOP1CYCSABCG2ENPP2TERT
SCHEMBL5067509 0.76 TERT (0.41) TOP1CYCSABCG2ENPP2TERT
SCHEMBL3421639 0.76 TERT (0.45) TOP1CYCSABCG2ENPP2TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518905-B2 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-14 — — US disclosed
US-20060209587-A1 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-09-21 — — US disclosed
US-7042755-B1 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-05-09 — — US disclosed
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