SCHEMBL4263830

SCHEMBL4263830

CC(=O)SCc1ccc(-c2c3nc(c(-c4c(C)cc(C)cc4C)c4ccc([nH]4)c(-c4c(C)cc(C)cc4C)c4nc(c(-c5c(C)cc(C)cc5C)c5ccc2[nH]5)C=C4)C=C3)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TOP1 P11387 4/20 0.46
▸ CYCS P99999 4/20 0.45
▸ ABCG2 Q9UNQ0 1/20 0.45
▸ ENPP2 Q13822 1/20 0.42
▸ TERT O14746 5/20 0.39
▸ KDM4E B2RXH2 1/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ APEX1 P27695 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ DUSP3 P51452 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ MCL1 Q07820 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4260911 0.94 TOP1 (0.41) TOP1CYCSABCG2ENPP2TERT
SCHEMBL4264116 0.89 TOP1 (0.44) TOP1CYCSABCG2ENPP2TERT
SCHEMBL4258798 0.88 TOP1 (0.43) TOP1CYCSABCG2ENPP2TERT
SCHEMBL4259964 0.83 TOP1 (0.49) TOP1CYCSABCG2ENPP2TERT
SCHEMBL79553 0.83 TOP1 (0.47) TOP1CYCSABCG2ENPP2TERT
SCHEMBL452959 0.80 TERT (0.45) TOP1CYCSABCG2ENPP2TERT
SCHEMBL1344998 0.79 TOP1 (0.62) TOP1CYCSABCG2ENPP2TERT
SCHEMBL4260949 0.78 TOP1 (0.45) TOP1CYCSABCG2ENPP2TERT
Magnesium SCHEMBL29489413 0.78 TERT (0.46) TOP1CYCSABCG2ENPP2TERT
SCHEMBL4266706 0.78 TOP1 (0.44) TOP1CYCSABCG2ENPP2TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518905-B2 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-14 — — US disclosed
US-20060209587-A1 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-09-21 — — US disclosed
US-7042755-B1 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-05-09 — — US disclosed
EP-1210714-A4 HIGH DENSITY NON-VOLATILE MEMORY DEVICE UNIV (US) 2006-01-04 — — EP disclosed
EP-1210714-A2 HIGH DENSITY NON-VOLATILE MEMORY DEVICE The Regents of the University of California (US) 2002-06-05 — — EP disclosed
WO-2001003126-A2 HIGH DENSITY NON-VOLATILE MEMORY DEVICE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-01-11 — — WO disclosed
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