Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 19/20 | 0.43 |
| ▸ | GSK3B | P49841 | 10/20 | 0.43 |
| ▸ | CLK2 | P49760 | 4/20 | 0.41 |
| ▸ | CLK3 | P49761 | 4/20 | 0.41 |
| ▸ | WNT1 | P04628 | 4/20 | 0.39 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL4222944 | 0.92 | UGCG (0.38) | DYRK1AGSK3BUGCG | |
| SCHEMBL1572715 | 0.86 | DYRK1A (0.51) | DYRK1AGSK3BCLK2CLK3 | |
| SCHEMBL1572791 | 0.82 | HAO1 (0.45) | DYRK1AGSK3BCLK2CLK3WNT1 | |
| SCHEMBL1572745 | 0.80 | GSK3B (0.43) | DYRK1AGSK3BCLK2CLK3UGCG | |
| SCHEMBL4529923 | 0.80 | CCNC (0.42) | DYRK1AWNT1UGCG | |
| SCHEMBL5038892 | 0.80 | DYRK1A (0.41) | DYRK1AGSK3BCLK2CLK3WNT1 | |
| SCHEMBL1572800 | 0.80 | DYRK1A (0.39) | DYRK1AGSK3BCLK2CLK3WNT1 | |
| SCHEMBL1175540 | 0.80 | DYRK1A (0.41) | DYRK1AGSK3BCLK2CLK3WNT1 | |
| SCHEMBL1175956 | 0.80 | DYRK1A (0.41) | DYRK1AGSK3BCLK2CLK3WNT1 | |
| SCHEMBL4232915 | 0.79 | GSK3B (0.46) | GSK3BUGCG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575960-B1 | 1,4-DIAZABICYCLO 3.2.2 NONANECARBOXAMIDE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2009-03-18 | — | — | EP | disclosed |