SCHEMBL4262000

SCHEMBL4262000

Cc1ccccc1C#Cc1[c]cccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.42
GRM5 P41594 5/20 0.41
FFAR1 O14842 7/20 0.36
FFAR4 Q5NUL3 2/20 0.36
CHRM2 P08172 1/20 0.36
S1PR1 P21453 1/20 0.36
FPR1 P21462 1/20 0.36
FPR3 P25089 1/20 0.36
GPR183 P32249 1/20 0.36
APLNR P35414 1/20 0.36
GPR65 Q8IYL9 1/20 0.36
KCNH2 Q12809 1/20 0.33
ACHE P22303 1/20 0.33
IKBKB O14920 1/20 0.32
GABRP O00591 1/20 0.31
GABRD O14764 1/20 0.31
GABRA1 P14867 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
GABRB3 P28472 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30666154 0.78 TSHR (0.62) TSHRGRM5FFAR1FFAR4CHRM2
SCHEMBL3644208 0.78 TSHR (0.62) TSHRGRM5FFAR1FFAR4CHRM2
SCHEMBL5403604 0.77 ALDH1A1 (0.47) GRM5FFAR1KCNH2
SCHEMBL6535731 0.77 KCNH2 (0.33) KCNH2
SCHEMBL27836394 0.77 GRM5 (0.44) TSHRGRM5FFAR1CHRM2
SCHEMBL21858053 0.74 CHAT (0.49) TSHRGRM5KCNH2
SCHEMBL21858922 0.74 ALDH1A1 (0.33) KCNH2
SCHEMBL21858113 0.74 GRM5 (0.42) GRM5FFAR1GABRG2GABRB3GABRA5
SCHEMBL20855041 0.74 NOS3 (0.35)
SCHEMBL2291999 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7518905-B2 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-04-14 US disclosed
US-20060209587-A1 High density memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-09-21 US disclosed
US-7042755-B1 High density non-volatile memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2006-05-09 US disclosed
EP-1210714-A4 HIGH DENSITY NON-VOLATILE MEMORY DEVICE UNIV (US) 2006-01-04 EP disclosed
WO-2001003126-A9 HIGH DENSITY NON-VOLATILE MEMORY DEVICE UNIV CALIFORNIA (US) 2002-08-01 WO disclosed
EP-1210714-A2 HIGH DENSITY NON-VOLATILE MEMORY DEVICE The Regents of the University of California (US) 2002-06-05 EP disclosed
WO-2001003126-A2 HIGH DENSITY NON-VOLATILE MEMORY DEVICE THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2001-01-11 WO disclosed