SCHEMBL4262834

SCHEMBL4262834

CCc1c(C(=O)OO)ccc(C(=O)OO)c1CC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.39
ALDH1A1 P00352 4/20 0.36
CA12 O43570 2/20 0.36
CA1 P00915 2/20 0.36
CA2 P00918 2/20 0.36
CA7 P43166 2/20 0.36
CA9 Q16790 2/20 0.36
CA14 Q9ULX7 2/20 0.36
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
MEN1 O00255 3/20 0.34
MAPT P10636 3/20 0.34
KMT2A Q03164 3/20 0.34
LMNA P02545 3/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
CNR2 P34972 1/20 0.34
CYP3A4 P08684 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3100735 0.92 GABRP (0.40) TSHRALDH1A1TDP1MEN1KMT2A
SCHEMBL29288249 0.90 CA12 (0.39) ALDH1A1CA12CA1CA2CA7
SCHEMBL8075157 0.87 TSHR (0.45) TSHRALDH1A1CA12CA1CA2
SCHEMBL28758608 0.85 MAPT (0.40) ALDH1A1CA12CA1CA2CA7
SCHEMBL18204383 0.83 RAB9A (0.39) TSHRALDH1A1CA12CA1CA2
SCHEMBL4408583 0.81 CA12 (0.46) TSHRALDH1A1CA12CA1CA2
SCHEMBL28813133 0.80 TSHR (0.38) TSHRALDH1A1CA12CA1CA2
SCHEMBL9255849 0.78 TSHR (0.36) TSHRALDH1A1CA12CA1CA2
SCHEMBL1018547 0.76 PARP1 (0.42) TSHRALDH1A1TDP1MEN1MAPT
SCHEMBL1532511 0.74 TSHR (0.50) TSHRALDH1A1TDP1L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109031794-B Reflecting sheet, backlight module and display device 合肥京东方光电科技有限公司 2024-01-30 CN disclosed
CN-217140323-U Outer circulation esterification reaction device 中国石油化工股份有限公司 2022-08-09 CN disclosed
CN-114635198-A Viscose elastic fiber and preparation method thereof 江苏环鼎纺织科技有限公司 2022-06-17 CN disclosed
US-20090173055-A1 COMPOSITE COTTON AND POLYESTER YARN AND METHOD FOR MAKING SAME SILVER SCOTT 2009-07-09 US disclosed
CN-100358933-C Fluorescent sensing materials made of conjugated polymer and process for preparing same UNIV FUDAN (CN) 2008-01-02 CN disclosed
CN-1942551-A New organic luminescent element CIBA SC HOLDING AG (CH) 2007-04-04 CN disclosed
CN-1827664-A Fluorescent sensing materials made of conjugated polymer and process for preparing same UNIV FUDAN (CN) 2006-09-06 CN disclosed
EP-0812818-B1 Esterification process ACMA LTD (GB) 2001-10-31 EP disclosed
EP-1035916-B1 ESTERIFICATION CATALYSTS ACMA LTD (GB) 2001-09-05 EP disclosed
EP-1120392-A1 Catalyst and organometallic composition ACMA Limited (GB) 2001-08-01 EP disclosed
US-6258878-B1 One-part moisture-curable hydrocarbon polymer composition DOW CORNING CORPORATION 2001-07-10 US disclosed
WO-2000058392-A1 ONE-PART MOISTURE-CURABLE HYDROCARBON POLYMER COMPOSITION DOW CORNING CORPORATION (US) 2000-10-05 WO disclosed
EP-1035916-A1 ESTERIFICATION CATALYSTS ACMA Limited (GB) 2000-09-20 EP disclosed
WO-1999028033-A1 ESTERIFICATION CATALYSTS ACMA LIMITED (GB) 1999-06-10 WO disclosed
US-5866710-A CATALYST COMPRISING THE REACTION PRODUCT OF AN ORTHOESTER OR A CONDENSED ORTHOESTER OF TITANIUM OR ZIRCONIUM, AN ALCOHOL CONTAINING AT LEAST TWO HYDROXYL GROUPS, A 2-HYDROXY ACID AND A BASE. TIOXIDE SPECIALTIES LIMITED (GB) 1999-02-02 US disclosed
EP-0812818-A1 Esterification process TIOXIDE SPECIALTIES LIMITED (GB) 1997-12-17 EP disclosed
EP-0005549-B1 PROCESS FOR MANUFACTURING TEXTILES COATED WITH POLYURETHANE FOAM Mobay Chemical Corporation (US) 1981-02-11 EP disclosed
EP-0005549-A2 Process for manufacturing textiles coated with polyurethane foam Mobay Chemical Corporation (US) 1979-11-28 EP disclosed