Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | CCR2 | P41597 | 1/20 | 0.44 |
| ▸ | CCR5 | P51681 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL4268033 | 0.88 | GUSB (0.45) | KDRMAPTSMN1; SMN2TP53CCR2 | |
| SCHEMBL3049443 | 0.82 | MAPT (0.49) | KDRMAPTSMN1; SMN2TP53CCR2 | |
| SCHEMBL3051396 | 0.78 | TP53 (0.55) | KDRMAPTSMN1; SMN2TP53CCR2 | |
| Ammonia Solution, Strong SCHEMBL4268234 | 0.76 | TP53 (0.52) | KDRMAPTSMN1; SMN2TP53CCR2 | |
| Ammonia Solution, Strong SCHEMBL4270918 | 0.75 | TUBB4A (0.48) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| Ammonia Solution, Strong SCHEMBL4275960 | 0.74 | MAPT (0.46) | KDRMAPTSMN1; SMN2TP53CCR2 | |
| SCHEMBL3055713 | 0.74 | MAPT (0.50) | MAPTSMN1; SMN2TP53CCR2CCR5 | |
| Ammonia Solution, Strong SCHEMBL4262270 | 0.74 | MAPT (0.53) | KDRMAPTSMN1; SMN2TP53CCR2 | |
| SCHEMBL3055646 | 0.74 | TP53 (0.58) | KDRMAPTSMN1; SMN2TP53CCR2 | |
| Ammonia Solution, Strong SCHEMBL4262241 | 0.73 | GUSB (0.49) | KDRMAPTSMN1; SMN2TP53CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090131445-A1 | Furazano '3, 4-B! Pyrazines and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-05-21 | — | — | US | claimed |
| US-20090131445-A1 | Furazano '3, 4-B! Pyrazines and Their Use as Anti-Tumor Agents | COMPASS PHARMACEUTICALS LLC (US) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131445-A1 | Furazano '3, 4-B! Pyrazines and Their Use as Anti-Tumor Agents | CDC73, RB1, CA5A | KDR 3420/4885MAPT 4220/4885SMN1; SMN2 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.