Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PHGDH | O43175 | 3/20 | 0.37 |
| ▸ | MGLL | Q99685 | 3/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134304 | 0.97 | TSHR (0.65) | TSHRMAPK1ALDH1A1LMNAPHGDH | |
| Methane SCHEMBL2159555 | 0.92 | TSHR (0.60) | TSHRMAPK1ALDH1A1LMNAPHGDH | |
| SCHEMBL24470878 | 0.81 | TSHR (0.46) | TSHRMAPK1ALDH1A1LMNAPHGDH | |
| SCHEMBL21221413 | 0.81 | PHGDH (0.50) | TSHRMAPK1ALDH1A1LMNAPHGDH | |
| SCHEMBL8104956 | 0.80 | TSHR (0.63) | TSHRMAPK1ALDH1A1LMNAMGLL | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL8541416 | 0.77 | TSHR (1.00) | TSHRMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9420118 | 0.77 | ALDH1A1 (0.49) | TSHRMAPK1ALDH1A1LMNAPHGDH | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL66482 | 0.77 | TSHR (1.00) | TSHRMAPK1ALDH1A1KMT2AMEN1 | |
| Butylate SCHEMBL5077084 | 0.77 | TSHR (0.54) | TSHRMAPK1ALDH1A1HSD17B10CA12 | |
| SCHEMBL11454569 | 0.77 | TSHR (0.59) | TSHRMAPK1ALDH1A1MGLLMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7626008-B2 | Anti-angiogenic polypeptides | WAISMAN DAVID M | 2009-12-01 | — | — | US | disclosed |
| CN-100491394-C | Anti-angiogenic polypeptides | DAVID M WAISMAN KASSAM GEETHA (CA) | 2009-05-27 | — | — | CN | disclosed |
| US-20090061510-A1 | Vectors, eukaryotic cells | WAISMAN DAVID M | 2009-03-05 | — | — | US | disclosed |
| US-7420036-B2 | Anti-angiogenic polypeptides | WAISMAN DAVID M | 2008-09-02 | — | — | US | disclosed |
| EP-1337548-B1 | ANTI-ANGIOGENIC POLYPEPTIDES | WAISMAN DAVID M (CA) | 2008-07-16 | — | — | EP | disclosed |
| EP-1337548-A4 | ANTI-ANGIOGENIC POLYPEPTIDES | WAISMAN DAVID M (CA) | 2005-01-12 | — | — | EP | disclosed |
| CN-1498223-A | Anti-angiogenic polypeptides | M | 2004-05-19 | — | — | CN | disclosed |
| US-20040082030-A1 | Anti-angiogenic polypeptides | WAISMAN DAVID M (CA) | 2004-04-29 | — | — | US | disclosed |
| EP-1337548-A2 | ANTI-ANGIOGENIC POLYPEPTIDES | Waisman, David M. (CA) | 2003-08-27 | — | — | EP | disclosed |
| WO-2002044328-A2 | ANTI-ANGIOGENIC POLYPEPTIDES | WAISMAN DAVID M (CA) | 2002-06-06 | — | — | WO | disclosed |