Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PHGDH | O43175 | 3/20 | 0.36 |
| ▸ | MGLL | Q99685 | 3/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL134304 | 0.95 | TSHR (0.65) | TSHRMAPK1ALDH1A1LMNAPHGDH | |
| SCHEMBL4263485 | 0.92 | TSHR (0.62) | TSHRMAPK1ALDH1A1LMNAPHGDH | |
| SCHEMBL24470878 | 0.79 | TSHR (0.46) | TSHRMAPK1ALDH1A1LMNAPHGDH | |
| SCHEMBL21221413 | 0.79 | PHGDH (0.50) | TSHRMAPK1ALDH1A1LMNAPHGDH | |
| SCHEMBL8104956 | 0.78 | TSHR (0.63) | TSHRMAPK1ALDH1A1LMNAMGLL | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL8541416 | 0.75 | TSHR (1.00) | TSHRMAPK1ALDH1A1KMT2AMEN1 | |
| S-Ethyl Dipropylcarbamothioate SCHEMBL66482 | 0.75 | TSHR (1.00) | TSHRMAPK1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9420118 | 0.75 | ALDH1A1 (0.49) | TSHRMAPK1ALDH1A1LMNAPHGDH | |
| Butylate SCHEMBL395574 | 0.75 | TSHR (0.54) | TSHRMAPK1ALDH1A1HSD17B10CA12 | |
| SCHEMBL11454569 | 0.74 | TSHR (0.59) | TSHRMAPK1ALDH1A1MGLLMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130231486-A1 | COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | MATRIX LABORATORIES LIMITED (IN) | 2013-09-05 | — | — | US | disclosed |
| US-8513427-B2 | Compounds for producing substituted sulfoxides, process for producing the same and use thereof | MATRIX LABORATORIES LIMITED (IN) | 2013-08-20 | — | — | US | disclosed |
| EP-2342193-B1 | NOVEL COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | MATRIX LAB LTD (IN) | 2013-06-05 | — | — | EP | disclosed |
| US-20110184182-A1 | COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | MATRIX LABORATORIES LIMITED (IN) | 2011-07-28 | — | — | US | disclosed |
| EP-2342193-A2 | NOVEL COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | Matrix Laboratories Limited (IN) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010035283-A2 | NOVEL COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | MATRIX LABORATORIES LIMITED (IN) | 2010-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130231486-A1 | COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | SQOR, SMOX, CBS | TSHR 3643/4885MAPK1 2238/4885ALDH1A1 248/4885 |
| US-20110184182-A1 | COMPOUNDS FOR PRODUCING SUBSTITUTED SULFOXIDES, PROCESS FOR PRODUCING THE SAME AND USE THEREOF | SQOR, SMOX, CBS | TSHR 3643/4885MAPK1 2238/4885ALDH1A1 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.