Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.47 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16177483 | 0.82 | PDK2 (0.55) | PDK2ESR1ESR2KDM4ESMN1; SMN2 | |
| SCHEMBL29756627 | 0.82 | PDK2 (0.55) | PDK2ESR1ESR2KDM4ESMN1; SMN2 | |
| SCHEMBL29375118 | 0.82 | PDK2 (0.55) | PDK2ESR1ESR2KDM4ESMN1; SMN2 | |
| SCHEMBL29615782 | 0.82 | PDK2 (0.55) | PDK2ESR1ESR2KDM4ESMN1; SMN2 | |
| SCHEMBL16176940 | 0.82 | PDK2 (0.55) | PDK2ESR1ESR2KDM4ESMN1; SMN2 | |
| SCHEMBL29493741 | 0.82 | PDK2 (0.55) | PDK2ESR1ESR2KDM4ESMN1; SMN2 | |
| SCHEMBL249 | 0.81 | SLC6A3 (0.73) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL29295035 | 0.80 | SLC6A3 (0.64) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL29294796 | 0.78 | SLC6A3 (0.61) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL29294780 | 0.77 | SLC6A3 (0.57) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9349960-B2 | Compounds and polymers which contain substituted indenofluorene derivatives as structural unit, process for the preparation thereof, and the use thereof as electronic devices and mixtures and solutions | MERCK PATENT GMBH (DE) | 2016-05-24 | — | — | US | disclosed |
| US-9349960-B2 | Compounds and polymers which contain substituted indenofluorene derivatives as structural unit, process for the preparation thereof, and the use thereof as electronic devices and mixtures and solutions | MERCK PATENT GMBH (DE) | 2016-05-24 | — | — | US | disclosed |
| US-20120061617-A1 | POLYMERS WHICH CONTAIN SUBSTITUTED INDENOFLUORENE DERIVATIVES AS STRUCTURAL UNIT, PROCESS FOR THE PREPARATION THEREOF, AND THE USE THEREOF | MERCK PATENT GMBH (DE) | 2012-03-15 | — | — | US | disclosed |
| US-20120061617-A1 | POLYMERS WHICH CONTAIN SUBSTITUTED INDENOFLUORENE DERIVATIVES AS STRUCTURAL UNIT, PROCESS FOR THE PREPARATION THEREOF, AND THE USE THEREOF | MERCK PATENT GMBH (DE) | 2012-03-15 | — | — | US | disclosed |
| WO-2010136110-A2 | POLYMERS COMPRISING SUBSTITUTED INDENOFLUORENE DERIVATES AS STRUCTURAL UNITS, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF | MERCK PATENT GMBH (DE) | 2010-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120061617-A1 | POLYMERS WHICH CONTAIN SUBSTITUTED INDENOFLUORENE DERIVATIVES AS STRUCTURAL UNIT, PROCESS FOR THE PREPARATION THEREOF, AND THE USE THEREOF | PPID, PCID2, OCIAD1 | SLC6A3 2056/4885SLC6A4 2001/4885SLC6A2 1717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.