Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.64 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.54 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.52 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.52 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10533851 | 0.94 | SLC6A3 (0.65) | SLC6A3SLC6A4SLC6A2CYP46A1ROCK2 | |
| SCHEMBL31316347 | 0.87 | SLC6A3 (0.56) | SLC6A3SLC6A4SLC6A2TSHRLMNA | |
| SCHEMBL31318316 | 0.87 | SLC6A3 (0.78) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL27843639 | 0.87 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL1775832 | 0.87 | SLC6A3 (0.74) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL68818 | 0.86 | SLC6A3 (0.73) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL8923988 | 0.86 | SLC6A3 (0.73) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| Phosphine SCHEMBL11469830 | 0.85 | SLC6A3 (0.72) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| SCHEMBL5700615 | 0.85 | SLC6A3 (0.72) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R | |
| Bicarbonate SCHEMBL27467504 | 0.85 | SLC6A3 (0.72) | SLC6A3SLC6A4SLC6A2ROCK2CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 139 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594589-A | 4. A , Preparation method of (E) -methyl biphenyl-2-carboxylic acid methyl ester | 济南大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-110372511-A | Utilize the method for 4 '-methyl biphenyl -2- carboxylate methyl ester waste residues preparation high-purity 4 '-methyl biphenyl -2- carboxylate methyl ester | 河南华商药业有限公司 | 2019-10-25 | — | — | CN | claimed |
| JP-9176103-A | — | — | None | — | — | JP | disclosed |
| CN-114436833-B | Preparation method of telmisartan key intermediate 4' -bromomethyl biphenyl-2-carboxylate | 南京红太阳医药研究院有限公司 | 2024-12-24 | — | — | CN | disclosed |
| CN-115959962-A | Visible light promoted halogenated alkane hydrodehalogenation method | 中国科学院兰州化学物理研究所 | 2023-04-14 | — | — | CN | disclosed |
| CN-109311813-B | Palladium-catalyzed meta-C-H functionalized universal ligands | 斯克利普斯研究院 | 2023-02-28 | — | — | CN | disclosed |
| CN-115594589-A | 4. A , Preparation method of (E) -methyl biphenyl-2-carboxylic acid methyl ester | 济南大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115594589-A | 4. A , Preparation method of (E) -methyl biphenyl-2-carboxylic acid methyl ester | 济南大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| US-11485721-B2 | Method for the metal-free preparation of a biaryl by a photosplicing reaction and their uses | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. Hans-Knöll-Institut (DE) | 2022-11-01 | — | — | US | disclosed |
| US-11485721-B2 | Method for the metal-free preparation of a biaryl by a photosplicing reaction and their uses | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. Hans-Knöll-Institut (DE) | 2022-11-01 | — | — | US | disclosed |
| CN-114436833-A | Preparation method of telmisartan key intermediate 4' -methylbiphenyl-2-carboxylic ester | 南京红太阳医药研究院有限公司 | 2022-05-06 | — | — | CN | disclosed |
| EP-0453210-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1991-10-23 | — | — | EP | disclosed |
| WO-1991007404-A1 | DIAZINE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-30 | — | — | WO | disclosed |
| EP-0420237-A1 | Biphenylmethane derivative, the use of it and pharmacological compositions containing same | Eisai Co., Ltd. (JP) | 1991-04-03 | — | — | EP | disclosed |
| EP-0412848-A2 | Quinoline derivatives, process for their preparation and their use as medicaments | ZENECA LIMITED (GB) | 1991-02-13 | — | — | EP | disclosed |
| EP-0399731-A1 | Azaindenes | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |
| EP-0399732-A1 | Benzimidazole derivatives | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |
| EP-0324377-A2 | Angiotensin II receptor blocking imidazoles and combinations thereof with diuretics and NSaids | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-19 | — | — | EP | disclosed |
| WO-1989006233-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES AND COMBINATIONS THEREOF WITH DIURETICS AND NSAIDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-07-13 | — | — | WO | disclosed |
| EP-0253310-A2 | Angiotensin II receptor blocking imidazoles | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11485721-B2 | Method for the metal-free preparation of a biaryl by a photosplicing reaction and their uses | CBR3, POR, CYP2F1 | SLC6A3 2793/4885SLC6A4 3042/4885SLC6A2 3114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.