SCHEMBL4264185

SCHEMBL4264185

COc1cnc(C)c(OC)n1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RECQL P46063 2/20 0.40
POLB P06746 2/20 0.38
TDP1 Q9NUW8 1/20 0.37
PDE10A Q9Y233 3/20 0.36
PIK3CA P42336 3/20 0.35
SIRT6 Q8N6T7 1/20 0.34
KMT2A Q03164 2/20 0.34
MEN1 O00255 1/20 0.34
HTT P42858 2/20 0.33
NNMT P40261 2/20 0.32
KDM4E B2RXH2 1/20 0.31
CACNA2D1 P54289 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
PDE2A O00408 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27895340 0.84 CACNA2D1 (0.37) RECQLPOLBPDE10APIK3CASIRT6
SCHEMBL28632167 0.82 RECQL (0.36) RECQLPOLBTDP1PDE10APIK3CA
SCHEMBL30505746 0.82 RECQL (0.36) RECQLPOLBTDP1PDE10APIK3CA
SCHEMBL17431082 0.81 NNMT (0.38) RECQLPDE10APIK3CASIRT6KMT2A
SCHEMBL14970085 0.80 CCR4 (0.43)
SCHEMBL4497174 0.79 CCR4 (0.37) RECQLPDE10APIK3CAKMT2AMEN1
SCHEMBL31538061 0.79 CCR4 (0.37) RECQLPDE10APIK3CAKMT2AMEN1
Pyrazine SCHEMBL27912592 0.78 PDE1A (0.34) RECQLKMT2AMEN1HTTCACNA2D1
SCHEMBL12767704 0.76 PIK3CA (0.41) RECQLPIK3CAKMT2AMEN1HTT
SCHEMBL26287829 0.76 CCR4 (0.42) PIK3CAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed