Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753558 | 1.00 | TSHR (0.32) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL37107 | 0.92 | CES2 (0.32) | — | |
| SCHEMBL2780314 | 0.87 | CES2 (0.35) | — | |
| SCHEMBL3988741 | 0.86 | — | — | |
| SCHEMBL19810336 | 0.85 | CES2 (0.38) | — | |
| SCHEMBL21900343 | 0.85 | CES2 (0.38) | — | |
| SCHEMBL19810337 | 0.85 | CES2 (0.38) | — | |
| SCHEMBL21111838 | 0.85 | CES2 (0.38) | — | |
| SCHEMBL2469918 | 0.85 | CES2 (0.38) | — | |
| SCHEMBL9417209 | 0.84 | THRB (0.36) | TSHRALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149375-A1 | IMPROVED ORGANOSILICON COMPOUNDS | RANKA, SEEMA, AJAY (IN) | 2008-12-11 | — | — | WO | claimed |
| US-20080009644-A1 | Organosilicon Compounds | ZYDEX INDUSTRIES | 2008-01-10 | — | — | US | claimed |
| US-7553983-B2 | Organosilicon compounds | ZYDEX INDUSTRIES (IN) | 2009-06-30 | — | — | US | disclosed |
| US-20080009644-A1 | Organosilicon Compounds | ZYDEX INDUSTRIES | 2008-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080009644-A1 | Organosilicon Compounds | CUL1, CUL3, MGAM | TSHR 4731/4885ALDH1A1 1076/4885MEN1 1105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.