Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105254 | 0.67 | LTB4R (0.40) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL5139179 | 0.64 | GABRR1 (0.72) | CYP1A2GABRR1LTA4HBLMACE2 | |
| SCHEMBL264775 | 0.61 | TSHR (0.68) | TSHR | |
| SCHEMBL473576 | 0.61 | TSHR (0.68) | TSHR | |
| SCHEMBL1073143 | 0.61 | TSHR (0.68) | TSHR | |
| SCHEMBL12670558 | 0.61 | TSHR (0.68) | TSHR | |
| Phosphine SCHEMBL27480220 | 0.60 | TSHR (0.66) | TSHR | |
| SCHEMBL24773894 | 0.59 | TSHR (0.46) | CYP1A2GABRR1LMNATSHR | |
| SCHEMBL17590311 | 0.59 | TSHR (0.50) | CYP1A2GABRR1TSHR | |
| SCHEMBL25181550 | 0.59 | TSHR (0.50) | CYP1A2GABRR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140364467-A1 | CHEMICAL INDUCERS OF NEUROGENESIS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-12-11 | — | — | US | disclosed |
| US-8778940-B2 | Chemical inducers of neurogenesis | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130143885-A1 | CHEMICAL INDUCERS OF NEUROGENESIS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2013-06-06 | — | — | US | disclosed |
| US-8193225-B2 | Isoxazole amides, derivatives and methods of chemical induction of neurogenesis | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-06-05 | — | — | US | disclosed |
| US-20090036451-A1 | Chemical inducers of neurogenesis | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2009-02-05 | — | — | US | disclosed |
| WO-2008046072-A2 | CHEMICAL INDUCERS OF NEUROGENESIS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364467-A1 | CHEMICAL INDUCERS OF NEUROGENESIS | DCX, NES, GAP43 | CYP1A2 2309/4885GABRR1 348/4885LTA4H 2856/4885 |
| US-20090036451-A1 | Chemical inducers of neurogenesis | DCX, NES, GAP43 | CYP1A2 2309/4885GABRR1 348/4885LTA4H 2856/4885 |
| US-20130143885-A1 | CHEMICAL INDUCERS OF NEUROGENESIS | DCX, NES, GAP43 | CYP1A2 2309/4885GABRR1 348/4885LTA4H 2856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.