SCHEMBL25181550

SCHEMBL25181550

Cc1ccc(CCC(C)C(=O)O)cc1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.50
▸ FFAR1 O14842 2/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ DPP4 P27487 1/20 0.46
▸ ALDH1A1 P00352 2/20 0.43
▸ POLB P06746 1/20 0.42
▸ HPGD P15428 1/20 0.42
▸ PTGFR P43088 1/20 0.42
▸ CYP1A2 P05177 2/20 0.42
▸ GABRR1 P24046 2/20 0.42
▸ CYP2A6 P11509 1/20 0.42
▸ TAAR1 Q96RJ0 1/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17590311 1.00 TSHR (0.50) TSHRFFAR1TDP1L3MBTL1DPP4
SCHEMBL13870218 0.89 LTB4R (0.48) FFAR1TDP1L3MBTL1ALDH1A1HPGD
SCHEMBL9511889 0.86 TSHR (0.47) TSHRFFAR1TDP1L3MBTL1DPP4
SCHEMBL27500484 0.85 OPRK1 (0.50) TSHRDPP4CYP1A2
SCHEMBL16080190 0.85 OPRK1 (0.50) TSHRDPP4CYP1A2
SCHEMBL1073143 0.84 TSHR (0.68) TSHRALDH1A1HPGDSMN1; SMN2
SCHEMBL473576 0.84 TSHR (0.68) TSHRALDH1A1HPGDSMN1; SMN2
SCHEMBL12670558 0.84 TSHR (0.68) TSHRALDH1A1HPGDSMN1; SMN2
SCHEMBL264775 0.84 TSHR (0.68) TSHRALDH1A1HPGDSMN1; SMN2
SCHEMBL2692838 0.83 TSHR (0.49) TSHRCYP1A2GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4709710-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY Arcturus Therapeutics, Inc. (US) 2026-03-18 — — EP disclosed
US-20240391870-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2024-11-28 — — US disclosed
WO-2024233750-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. (US) 2024-11-14 — — WO disclosed
EP-4430026-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY Arcturus Therapeutics, Inc. (US) 2024-09-18 — — EP disclosed
CN-118451059-A Ionizable cationic lipids for RNA delivery 阿克丘勒斯治疗公司 2024-08-06 — — CN disclosed
WO-2024148312-A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR AMINO ACID SYNTHESIS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-07-11 — — WO disclosed
US-20230295081-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2023-09-21 — — US disclosed
US-20230295081-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2023-09-21 — — US disclosed
US-20230295081-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2023-09-21 — — US disclosed
WO-2023086514-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. (US) 2023-05-19 — — WO disclosed
WO-2023086514-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. (US) 2023-05-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391870-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY NSUN3, POLRMT, NPC1L1 TSHR 1676/4885FFAR1 1510/4885TDP1 2944/4885
US-20230295081-A1 IONIZABLE CATIONIC LIPIDS FOR RNA DELIVERY NSUN3, POLRMT, NPC1L1 TSHR 1676/4885FFAR1 1510/4885TDP1 2944/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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