Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.81 |
| ▸ | NPC1 | O15118 | 5/20 | 0.81 |
| ▸ | RAB9A | P51151 | 5/20 | 0.81 |
| ▸ | MAPT | P10636 | 3/20 | 0.81 |
| ▸ | MEN1 | O00255 | 2/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.81 |
| ▸ | CASP3 | P42574 | 1/20 | 0.73 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.73 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.73 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.73 |
| ▸ | CA2 | P00918 | 2/20 | 0.71 |
| ▸ | CA12 | O43570 | 1/20 | 0.71 |
| ▸ | CA1 | P00915 | 1/20 | 0.71 |
| ▸ | CA9 | Q16790 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 7/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | AXL | P30530 | 1/20 | 0.61 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.56 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15058692 | 0.92 | KDM4E (0.74) | KDM4ENPC1RAB9AMAPTMEN1 | |
| Formic Acid SCHEMBL28953808 | 0.91 | KDM4E (0.68) | KDM4ENPC1RAB9AMAPTMEN1 | |
| SCHEMBL15059222 | 0.90 | KDM4E (0.72) | KDM4ENPC1RAB9AMAPTMEN1 | |
| SCHEMBL6118259 | 0.90 | KDM4E (0.72) | KDM4ENPC1RAB9AMAPTMEN1 | |
| SCHEMBL15058186 | 0.90 | KDM4E (0.72) | KDM4ENPC1RAB9AMAPTMEN1 | |
| SCHEMBL10793244 | 0.90 | KDM4E (0.72) | KDM4ENPC1RAB9AMAPTMEN1 | |
| SCHEMBL1429201 | 0.90 | NPC1 (1.00) | KDM4ENPC1RAB9AMAPTMEN1 | |
| SCHEMBL11651810 | 0.88 | KDM4E (0.67) | KDM4ENPC1RAB9AMAPTMEN1 | |
| SCHEMBL10799107 | 0.88 | KDM4E (0.73) | KDM4ENPC1RAB9AMAPTMEN1 | |
| SCHEMBL15058354 | 0.87 | KDM4E (0.72) | KDM4ENPC1RAB9AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410120-A | 2-phenylindole amide antitumor compound and application thereof | 四川农业大学 | 2023-07-11 | — | — | CN | disclosed |
| CN-107118145-B | Method for cyclizing and synthesizing indole under co-catalysis of palladium-organic nitrite | 中国科学技术大学 | 2020-05-05 | — | — | CN | disclosed |
| CN-107118145-A | A kind of method of the Cyclization indoles of palladium organic nitroso hydrochlorate co-catalysis | 中国科学技术大学 | 2017-09-01 | — | — | CN | disclosed |
| US-9334275-B2 | Processes for preparing indoles | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-05-10 | — | — | US | disclosed |
| US-9334275-B2 | Processes for preparing indoles | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-05-10 | — | — | US | disclosed |
| US-20150005494-A1 | PROCESSES FOR PREPARING INDOLES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-01 | — | — | US | disclosed |
| US-20150005494-A1 | PROCESSES FOR PREPARING INDOLES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2015-01-01 | — | — | US | disclosed |
| WO-2013095304-A1 | PROCESSES FOR PREPARING INDOLES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-06-27 | — | — | WO | disclosed |
| WO-2013095304-A1 | PROCESSES FOR PREPARING INDOLES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2013-06-27 | — | — | WO | disclosed |
| US-20090062236-A1 | Programmable genotoxic agents and uses therefor | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-03-05 | — | — | US | disclosed |
| WO-1995030442-A1 | PROGRAMMABLE GENOTOXIC AGENTS AND USES THEREFOR | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 1995-11-16 | — | — | WO | disclosed |
| US-5244860-A | PRESSURE-SENSITIVE RECORDING AND TRANSFER MATERIAL | CIBA-GEIGY CORPORATION (US) | 1993-09-14 | — | — | US | disclosed |
| EP-0373110-B1 | PRESSURE-SENSITIVE OR HEAT-SENSITIVE RECORDING MATERIAL | CIBA-GEIGY AG (CH) | 1993-04-21 | — | — | EP | disclosed |
| EP-0465403-A1 | Pressure sensitive recording and transfer material | CIBA-GEIGY AG (CH) | 1992-01-08 | — | — | EP | disclosed |
| EP-0465402-A1 | Heat sensitive recording material | CIBA-GEIGY AG (CH) | 1992-01-08 | — | — | EP | disclosed |
| EP-0463987-A1 | Pressure sensitive recording material | CIBA-GEIGY AG (CH) | 1992-01-02 | — | — | EP | disclosed |
| US-5024988-A | Color reaction system comprising a polycyclic heterocyclic compound, a leuko dye to form a chromogen with the first compound, a Lewis acid and developer | CIBA-GEIGY CORPORATION (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0373110-A2 | Pressure-sensitive or heat-sensitive recording material | CIBA-GEIGY AG (CH) | 1990-06-13 | — | — | EP | disclosed |
| US-4661511-A | ANTITUMOR AGENTS | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1987-04-28 | — | — | US | disclosed |
| US-4543360-A | ANTIESTROGENS, ANTITUMOR | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1985-09-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150005494-A1 | PROCESSES FOR PREPARING INDOLES | IDO1, INMT, IDO2 | KDM4E 2552/4885NPC1 3955/4885RAB9A 1761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.