Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | CASP3 | P42574 | 1/20 | 0.69 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.69 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.69 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | ITK | Q08881 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27944096 | 0.94 | NPC1 (0.88) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL15073408 | 0.90 | KDM4E (0.82) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL4264688 | 0.90 | KDM4E (0.81) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL3009057 | 0.89 | KDM4E (0.79) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL8995284 | 0.87 | KDM4E (0.76) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL3699661 | 0.87 | KDM4E (0.77) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL10832443 | 0.86 | NPC1 (0.75) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL15058692 | 0.85 | KDM4E (0.74) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL10799107 | 0.85 | KDM4E (0.73) | NPC1RAB9AKDM4EMAPTMEN1 | |
| SCHEMBL15073440 | 0.84 | KDM4E (0.73) | NPC1RAB9AKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113201526-B | Difunctional photo-enzyme synergistic catalyst and preparation method and application thereof | 东南大学 | 2024-04-09 | — | — | CN | claimed |
| CN-113201526-A | Bifunctional photo-enzyme synergistic catalyst and preparation method and application thereof | 东南大学 | 2021-08-03 | — | — | CN | claimed |
| US-20250186411-A1 | Methods of Treating Disorders Associated with Overactivation of IKKB | US GOV VETERANS AFFAIRS (US) | 2025-06-12 | — | — | US | disclosed |
| CN-118221563-A | Synthesis method of 2-aryl indole | 南京工业大学 | 2024-06-21 | — | — | CN | disclosed |
| CN-113201526-B | Difunctional photo-enzyme synergistic catalyst and preparation method and application thereof | 东南大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-113248419-A | Synthesis method of novel HuR inhibitor 1-benzenesulfonyl-3-phenylindole-4, 5-dione | 云南中医药大学 | 2021-08-13 | — | — | CN | disclosed |
| CN-113201526-A | Bifunctional photo-enzyme synergistic catalyst and preparation method and application thereof | 东南大学 | 2021-08-03 | — | — | CN | disclosed |
| CN-108863894-B | Method for directly synthesizing indole from nitrile | 中国科学技术大学 | 2020-08-14 | — | — | CN | disclosed |
| US-9540400-B2 | Compounds as diacylglycerol acyltransferase inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-01-10 | — | — | US | disclosed |
| US-9540400-B2 | Compounds as diacylglycerol acyltransferase inhibitors | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2017-01-10 | — | — | US | disclosed |
| US-20160200736-A1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2016-07-14 | — | — | US | disclosed |
| US-20020103383-A1 | Selective 5-HT6 receptor ligands | GLENNON RICHARD A (US) | 2002-08-01 | — | — | US | disclosed |
| US-20020103382-A1 | Selective 5-HT6 receptor ligands | GLENNON RICHARD A (US) | 2002-08-01 | — | — | US | disclosed |
| US-6403808-B1 | TREATING MENTAL DISORDERS | VIRGINIA COMMONWEALTH UNIVERSITY | 2002-06-11 | — | — | US | disclosed |
| EP-1149078-A1 | SELECTIVE 5-HT 6? RECEPTOR LIGANDS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2001-10-31 | — | — | EP | disclosed |
| WO-2000034242-A1 | SELECTIVE 5-HT6 RECEPTOR LIGANDS | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2000-06-15 | — | — | WO | disclosed |
| US-4113736-A | NONTOXIC POLYMER STABILIZERS | S. A. LABAZ (BE) | 1978-09-12 | — | — | US | disclosed |
| US-4104268-A | POLYACRYLONITRILE, POLYESTERS, POLYAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4006127-A | Cationic diazacyanine dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |
| US-3987059-A | ALKYL LITHIUM, CYCLIZATION, DEMETALLIZATION | SANDOZ, INC. (US) | 1976-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160200736-A1 | NOVEL COMPOUNDS AS DIACYLGLYCEROL ACYLTRANSFERASE INHIBITORS | DGAT1, DGAT2, LCAT | NPC1 133/4885RAB9A 3131/4885KDM4E 3858/4885 |
| US-20020103382-A1 | Selective 5-HT6 receptor ligands | HTR6, HTR4, HTR5A | NPC1 2037/4885RAB9A 2703/4885KDM4E 3690/4885 |
| US-20250186411-A1 | Methods of Treating Disorders Associated with Overactivation of IKKB | NFKBIA, IKBKG, IKBKB | NPC1 1123/4885RAB9A 3272/4885KDM4E 2712/4885 |
| US-20020103383-A1 | Selective 5-HT6 receptor ligands | HTR6, HTR4, HTR5A | NPC1 2037/4885RAB9A 2703/4885KDM4E 3690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.