Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483681 | 0.87 | ALOX5AP (0.40) | ALOX5APHCRTR2PIM1 | |
| SCHEMBL1483313 | 0.87 | ROCK1 (0.36) | — | |
| Hydrochloric Acid SCHEMBL1484299 | 0.86 | ROCK1 (0.35) | — | |
| SCHEMBL2818737 | 0.71 | ROCK1 (0.33) | — | |
| SCHEMBL4460733 | 0.70 | KDR (0.33) | ALOX5AP | |
| SCHEMBL5216499 | 0.70 | ALOX5AP (0.38) | ALOX5APHCRTR2 | |
| Bromide SCHEMBL667967 | 0.70 | ROCK2 (0.33) | — | |
| SCHEMBL667704 | 0.69 | MAPT (0.38) | — | |
| Bromide SCHEMBL4477940 | 0.69 | ALOX5AP (0.37) | ALOX5APHCRTR2 | |
| SCHEMBL1483337 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1915375-B1 | DERIVATIVES OF 5-PYRIDINYL-1-AZABICYCLO[3.2.1]OCTANE, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI AVENTIS (FR) | 2009-10-07 | — | — | EP | disclosed |