Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 7/20 | 0.92 |
| ▸ | TSHR | P16473 | 1/20 | 0.92 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.63 |
| ▸ | BAX | Q07812 | 1/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL179902 | 1.00 | LTA4H (0.92) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL28009593 | 0.96 | LTA4H (0.86) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL12286 | 0.96 | LTA4H (1.00) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL2461810 | 0.96 | LTA4H (1.00) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL9061108 | 0.96 | LTA4H (1.00) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL4950525 | 0.96 | LTA4H (1.00) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL10621546 | 0.92 | LTA4H (0.92) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL2886896 | 0.92 | LTA4H (0.92) | LTA4HTSHRNR1H2BAXMAOA | |
| Diphenylether SCHEMBL11777679 | 0.92 | LTA4H (0.92) | LTA4HTSHRNR1H2BAXMAOA | |
| SCHEMBL22129853 | 0.92 | LTA4H (0.92) | LTA4HTSHRNR1H2BAXMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11161818-B2 | Quinolone derivatives, preparation methods and application thereof | HANGZHOU NORMAL UNIVERSITY (CN) | 2021-11-02 | — | — | US | claimed |
| US-20210198207-A1 | QUINOLONE DERIVATIVES, PREPARATION METHODS AND APPLICATION THEREOF | HANGZHOU NORMAL UNIVERSITY (CN) | 2021-07-01 | — | — | US | claimed |
| CN-111018778-B | Quinolone derivative and preparation method and application thereof | 杭州师范大学 | 2020-11-06 | — | — | CN | claimed |
| CN-111018778-A | Quinolone derivative and preparation method and application thereof | 杭州师范大学 | 2020-04-17 | — | — | CN | claimed |
| CN-107344731-B | A kind of preparation method of the water-soluble Superparamagnetic Fe3O4 nanoparticles of single layer cladding | 南京大学 | 2019-06-21 | — | — | CN | claimed |
| CN-107344731-A | A kind of preparation method of the water-soluble SPIO of individual layer cladding | 南京大学 | 2017-11-14 | — | — | CN | claimed |
| CN-106519217-A | Method for preparing polyamide graft-modified halogen-free flame retardant through reactive extrusion | 扬州赛尔达尼龙制造有限公司 | 2017-03-22 | — | — | CN | claimed |
| CN-103930095-A | Eutectic mixture for pulmonary administration | PROSONIX LTD | 2014-07-16 | — | — | CN | claimed |
| CN-103648488-A | Pharmaceutical compositions and use in treating cough conditions | BIOCOPEA LTD | 2014-03-19 | — | — | CN | claimed |
| CN-102753174-A | Pharmaceutical combinations of theobromine and their use in therapy | BIOCOPEA LTD | 2012-10-24 | — | — | CN | claimed |
| US-5340905-A | Using a quaternary ammonium or phosphonium compound as catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-23 | — | — | US | claimed |
| US-20240282503-A1 | MAGNETIC PARTICLES, DUST CORE, AND COIL COMPONENT | MURATA MANUFACTURING CO., LTD. (JP) | 2024-08-22 | — | — | US | disclosed |
| US-20240240043-A1 | INKJET PRIMER COMPOSITIONS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2024-07-18 | — | — | US | disclosed |
| US-20240228805-A1 | INKJET PRIMER COMPOSITIONS CONTAINING NANOCELLULOSE | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS COLLATERAL AGENT | 2024-07-11 | — | — | US | disclosed |
| EP-4397728-A1 | INKJET PRIMER COMPOSITIONS CONTAINING NANOCELLULOSE | Xerox Corporation (US) | 2024-07-10 | — | — | EP | disclosed |
| US-5340905-A | Using a quaternary ammonium or phosphonium compound as catalyst | BAYER AKTIENGESELLSCHAFT (DE) | 1994-08-23 | — | — | US | disclosed |
| US-4830850-A | CONDITIONERS, SOFTENERS, PRESERVATIVES | GAF CORPORATION (US) | 1989-05-16 | — | — | US | disclosed |
| US-4287052-A | FOR BENEFICIATING SILICEOUS MINERAL ORES | THE DOW CHEMICAL COMPANY (US) | 1981-09-01 | — | — | US | disclosed |
| US-4287052-A | FOR BENEFICIATING SILICEOUS MINERAL ORES | THE DOW CHEMICAL COMPANY (US) | 1981-09-01 | — | — | US | disclosed |
| US-4287052-A | FOR BENEFICIATING SILICEOUS MINERAL ORES | THE DOW CHEMICAL COMPANY (US) | 1981-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11161818-B2 | Quinolone derivatives, preparation methods and application thereof | NQO2, MRPL21, TOP1 | LTA4H 2366/4885TSHR 4650/4885NR1H2 2348/4885 |
| US-20210198207-A1 | QUINOLONE DERIVATIVES, PREPARATION METHODS AND APPLICATION THEREOF | NQO2, MRPL21, TOP1 | LTA4H 2366/4885TSHR 4650/4885NR1H2 2348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.