Diphenylether

Diphenylether

SCHEMBL9061108

c1ccc(Oc2ccccc2)cc1.c1ccc(Oc2ccccc2)cc1.c1ccc(Oc2ccccc2)cc1.c1ccc(Oc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 1.00
TSHR P16473 1/20 1.00
NR1H2 P55055 1/20 0.67
BAX Q07812 1/20 0.67
MAOA P21397 1/20 0.67
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
MAOB P27338 1/20 0.57
CA4 P22748 1/20 0.53
GSTP1 P09211 1/20 0.52
SOS1 Q07889 1/20 0.52
CA9 Q16790 1/20 0.52
PARP10 Q53GL7 1/20 0.52
PLA2G2A P14555 1/20 0.52
MEN1 O00255 1/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
KMT2A Q03164 1/20 0.50
NLRP3 Q96P20 1/20 0.50
SRD5A2 P31213 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylether SCHEMBL2461810 1.00 LTA4H (1.00) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL4950525 1.00 LTA4H (1.00) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL12286 1.00 LTA4H (1.00) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL2886896 0.96 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL4265157 0.96 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL10621546 0.96 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL11777679 0.96 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL22129853 0.96 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL989476 0.96 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA
Diphenylether SCHEMBL179902 0.96 LTA4H (0.92) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5589219-A POLYOLEFIN INSULATING COATING SUMITOMO ELECTRIC INDUSTRIES, LTD. (JP) 1996-12-31 US disclosed