Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 9/20 | 0.60 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.60 |
| ▸ | MMP13 | P45452 | 2/20 | 0.60 |
| ▸ | MMP14 | P50281 | 2/20 | 0.60 |
| ▸ | MMP9 | P14780 | 5/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 10/20 | 0.55 |
| ▸ | PTPRF | P10586 | 1/20 | 0.55 |
| ▸ | PTPRA | P18433 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.54 |
| ▸ | MMP7 | P09237 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265160 | 1.00 | MMP2 (0.60) | MMP2ADAMTS4MMP13MMP14MMP9 | |
| SCHEMBL4271267 | 0.94 | MMP2 (0.66) | MMP2ADAMTS4MMP13MMP14MMP9 | |
| SCHEMBL4271261 | 0.94 | MMP2 (0.66) | MMP2ADAMTS4MMP13MMP14MMP9 | |
| SCHEMBL4273033 | 0.91 | MMP2 (0.56) | MMP2ADAMTS4MMP13MMP14MMP9 | |
| SCHEMBL4273027 | 0.91 | MMP2 (0.56) | MMP2ADAMTS4MMP13MMP14MMP9 | |
| SCHEMBL5766794 | 0.89 | PTPN1 (0.54) | MMP2ADAMTS4MMP13MMP14PTPN1 | |
| SCHEMBL5767364 | 0.86 | PTPN1 (0.51) | MMP2ADAMTS4MMP13MMP14PTPN1 | |
| SCHEMBL4265329 | 0.86 | PTPN1 (0.57) | MMP2ADAMTS4MMP13MMP14MMP9 | |
| SCHEMBL4263270 | 0.85 | PTPN1 (0.54) | MMP2ADAMTS4MMP13MMP14MMP9 | |
| SCHEMBL4263267 | 0.85 | PTPN1 (0.54) | MMP2ADAMTS4MMP13MMP14MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090082392-A1 | Substituted Carboxylic Acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC | 2009-03-26 | — | — | US | claimed |
| US-20040266788-A1 | Substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC | 2004-12-30 | — | — | US | claimed |
| US-20090082392-A1 | Substituted Carboxylic Acids | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY LLC | 2009-03-26 | — | — | US | disclosed |
| US-7358364-B2 | treatment of diabetes and/or cancer; useful in the treatment of syndrome X; capable of inhibiting Protein tyrosine phosphatase | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2008-04-15 | — | — | US | disclosed |
| US-20040266788-A1 | Substituted carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC | 2004-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040266788-A1 | Substituted carboxylic acids | PTP4A1, PTPRS, G6PC1 | MMP2 3873/4885ADAMTS4 4593/4885MMP13 4092/4885 |
| US-20090082392-A1 | Substituted Carboxylic Acids | PTPRJ, PTPRS, PTPRG | MMP2 3614/4885ADAMTS4 4500/4885MMP13 4095/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.