Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 11/20 | 0.61 |
| ▸ | KDR | P35968 | 6/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.59 |
| ▸ | SRC | P12931 | 3/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357880 | 0.90 | RIPK2 (0.72) | RIPK2KDRSRCLCKTGFBR1 | |
| SCHEMBL4265907 | 0.90 | RIPK2 (0.61) | RIPK2KDRPDGFRBSRCLCK | |
| SCHEMBL4261925 | 0.89 | RIPK2 (0.69) | RIPK2KDRPDGFRBSRCLCK | |
| SCHEMBL4263207 | 0.87 | RIPK2 (0.56) | RIPK2KDRPDGFRBSRCLCK | |
| SCHEMBL4257241 | 0.86 | RIPK2 (0.55) | RIPK2KDRPDGFRBSRCLCK | |
| SCHEMBL4261322 | 0.85 | RIPK2 (0.59) | RIPK2SRCKCNH2 | |
| SCHEMBL4262460 | 0.85 | RIPK2 (0.74) | RIPK2KDRSRCLCKTGFBR1 | |
| SCHEMBL6613867 | 0.84 | KDR (0.62) | KDRPDGFRB | |
| SCHEMBL4255774 | 0.84 | RIPK2 (0.59) | RIPK2KDRPDGFRBSRCLCK | |
| SCHEMBL4257460 | 0.82 | RIPK2 (0.62) | RIPK2KDRPDGFRBSRCLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090012309-A1 | CHEMICAL COMPOUNDS | ADAMS JERRY LEROY | 2009-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012309-A1 | CHEMICAL COMPOUNDS | CYP11B2, CYP3A43, CYP3A5 | RIPK2 2720/4885KDR 3847/4885PDGFRB 2728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.