Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29184833 | 0.87 | NPC1 (0.41) | NPC1RAB9ALMNAPOLBMAPT | |
| SCHEMBL8204058 | 0.84 | NPC1 (0.48) | NPC1RAB9ALMNAPOLBMAPT | |
| SCHEMBL1264000 | 0.83 | NPC1 (0.36) | NPC1RAB9ALMNAPOLBMAPT | |
| SCHEMBL301989 | 0.83 | NPC1 (0.47) | NPC1RAB9ALMNAPOLBMAPT | |
| SCHEMBL6419522 | 0.83 | NPC1 (0.49) | NPC1RAB9ALMNAPOLBMAPT | |
| SCHEMBL29454650 | 0.81 | NPC1 (0.34) | NPC1RAB9ALMNAPOLBKDM4E | |
| SCHEMBL19547230 | 0.81 | NPC1 (0.37) | NPC1RAB9ALMNAPOLBMAPT | |
| SCHEMBL29379341 | 0.81 | NPC1 (0.37) | NPC1RAB9ALMNAPOLBMAPT | |
| SCHEMBL16540651 | 0.81 | CYP3A4 (0.47) | NPC1RAB9ALMNAPOLBMAPT | |
| SCHEMBL28904542 | 0.80 | NPC1 (0.42) | NPC1RAB9ALMNAPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841970-B1 | LIGHT-RESISTANT POLYURETHANE COMPOUND | COVESTRO DEUTSCHLAND AG (DE) | 2017-11-08 | — | — | EP | disclosed |
| EP-2751618-A2 | COMPOSITE RESIN COMPOSITION AND METHOD FOR PRODUCING DENTAL COMPONENTS BY MEANS OF STEREO-LITHOGRAPHY | Ivoclar Vivadent AG (LI) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013153183-A2 | COMPOSITE RESIN COMPOSITION AND METHOD FOR PRODUCING DENTAL COMPONENTS BY MEANS OF STEREO-LITHOGRAPHY | IVOCLAR VIVADENT AG (LI) | 2013-10-17 | — | — | WO | disclosed |
| US-20090000727-A1 | HARDCOAT LAYERS ON RELEASE LINERS | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-01 | — | — | US | disclosed |