SCHEMBL301989

SCHEMBL301989

Cc1ccccc1C(C)c1cc(C(C)c2ccccc2C)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 6/20 0.47
RAB9A P51151 6/20 0.47
LMNA P02545 1/20 0.43
POLB P06746 3/20 0.42
ALDH1A1 P00352 4/20 0.37
MAPT P10636 4/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
HPGD P15428 3/20 0.37
NPSR1 Q6W5P4 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
KDM4E B2RXH2 4/20 0.36
GAA P10253 2/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
MEN1 O00255 2/20 0.32
USP2 O75604 2/20 0.32
KMT2A Q03164 2/20 0.32
PPARG P37231 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL947944 0.88 NPC1 (0.45) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL466590 0.85 NPC1 (0.47) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL4265490 0.83 NPC1 (0.39) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL9183011 0.80 NPC1 (0.58) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL4357048 0.77 NPC1 (0.50) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL11620211 0.77 NPC1 (0.45) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL11615531 0.76 NPC1 (0.50) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL9467622 0.76 NPC1 (0.52) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL7172078 0.75 NPC1 (0.48) NPC1RAB9ALMNAPOLBALDH1A1
SCHEMBL10484328 0.74 NPC1 (0.55) NPC1RAB9ALMNAPOLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4852410-B2 2012-01-11 JP claimed
EP-1599744-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES, INC. (US) 2005-11-30 EP claimed
WO-2004077097-A2 SELF-INDICATING RADIATION ALERT DOSIMETER JP LABORATORIES INC. (US) 2004-09-10 WO claimed
EP-4395982-A1 TUBE AND METHOD FOR MAKING SAME Saint-Gobain Performance Plastics Corporation (US) 2024-07-10 EP disclosed
EP-4347711-A1 POLYMERIC COMPOSITION AND PRODUCT COMPRISING THE POLYMERIC COMPOSITION MAIP S.r.l. (IT) 2024-04-10 EP disclosed
WO-2023156239-A1 Laminated glazing comprising a bird protection pattern KURARAY EUROPE GMBH (DE) 2023-08-24 WO disclosed
EP-3708386-B1 NONPNEUMATIC TIRE BRIDGESTONE CORP (JP) 2023-06-07 EP disclosed
US-20230167337-A1 ADHESIVE SHEET NITTO DENKO CORPORATION (JP) 2023-06-01 US disclosed
EP-4178797-A1 LAMINATED GLASS WITH ANTI-COUNTERFEITING PROPERTIES Kuraray Europe GmbH (DE) 2023-05-17 EP disclosed
WO-2023034784-A1 TUBE AND METHOD FOR MAKING SAME SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2023-03-09 WO disclosed
WO-2022254348-A1 POLYMERIC COMPOSITION AND PRODUCT COMPRISING THE POLYMERIC COMPOSITION MAIP S.R.L. (IT) 2022-12-08 WO disclosed
EP-3440122-B1 COLOURED PLASTICS BASED ON CROSSLINKED POLYISOCYANATES COVESTRO DEUTSCHLAND AG (DE) 2019-08-14 EP disclosed
US-20180289719-A1 COMPOSITION KOWA COMPANY, LTD. (JP) 2018-10-11 US disclosed
WO-2014110203-A1 POLYMERS POLYMERIZED FROM AT LEAST FOUR MONOMERS, AND COMPOSITIONS AND USES THEREOF ISP INVESTMENTS INC. (US) 2014-07-17 WO disclosed
EP-2751618-A2 COMPOSITE RESIN COMPOSITION AND METHOD FOR PRODUCING DENTAL COMPONENTS BY MEANS OF STEREO-LITHOGRAPHY Ivoclar Vivadent AG (LI) 2014-07-09 EP disclosed
WO-2013153183-A2 COMPOSITE RESIN COMPOSITION AND METHOD FOR PRODUCING DENTAL COMPONENTS BY MEANS OF STEREO-LITHOGRAPHY IVOCLAR VIVADENT AG (LI) 2013-10-17 WO disclosed
EP-2202064-A1 LIGHT-RESISTANT FILM Teijin Dupont Films Japan Limited (JP) 2010-06-30 EP disclosed
EP-1951529-A2 FLUORESCENT ARTICLE HAVING MULTIPLE LAYERS AVERY DENNISON CORPORATION (US) 2008-08-06 EP disclosed
WO-2007050696-A2 FLUORESCENT ARTICLE HAVING MULTIPLE LAYERS AVERY DENNISON CORPORATION (US) 2007-05-03 WO disclosed
US-5651926-A SYNERGISTIC SUPPRESSION WITH CYCLIC IMINO ESTERS AND QUINOXALINES TEIJIN LIMITED (JP) 1997-07-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180289719-A1 COMPOSITION PTGS1, PTGER1, NDUFA1 NPC1 1262/4885RAB9A 3622/4885LMNA 429/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.