SCHEMBL426573

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL428645	0.86	KMT2A (0.81)	KMT2AMEN1MAPTKDM4EPOLB
	SCHEMBL17791869	0.85	KDM4E (0.57)	KMT2AMEN1MAPTKDM4EPOLB
	SCHEMBL18537673	0.83	MAPT (0.88)	KMT2AMEN1MAPTKDM4EPOLB
	SCHEMBL13568307	0.82	KMT2A (0.76)	KMT2AMEN1MAPTKDM4EPOLB
	SCHEMBL14954964	0.82	LIMK1 (0.84)	KMT2AMEN1MAPTKDM4EPOLB
	SCHEMBL29558180	0.82	MAPT (1.00)	KMT2AMEN1MAPTKDM4EPOLB
	SCHEMBL13186381	0.82	MAPT (0.86)	KMT2AMEN1MAPTKDM4EPOLB
	SCHEMBL19000365	0.82	MAPT (0.86)	KMT2AMEN1MAPTKDM4EPOLB
	SCHEMBL19853111	0.82	MAPT (1.00)	KMT2AMEN1MAPTKDM4EPOLB
	SCHEMBL430632	0.82	KMT2A (0.64)	KMT2AMEN1MAPTKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.