SCHEMBL4265760

SCHEMBL4265760

c1ccc(COc2cncc(OCc3ccccc3)n2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 1/20 0.48
ALOX5 P09917 1/20 0.47
GABRG2 P18507 2/20 0.46
GABRB3 P28472 2/20 0.46
GABRA5 P31644 2/20 0.46
GABRA3 P34903 2/20 0.46
GABRP O00591 1/20 0.46
GABRD O14764 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB1 P18505 1/20 0.46
GABRA2 P47869 1/20 0.46
GABRB2 P47870 1/20 0.46
GABRA4 P48169 1/20 0.46
GABRE P78334 1/20 0.46
GABRA6 Q16445 1/20 0.46
GABRG1 Q8N1C3 1/20 0.46
GABRG3 Q99928 1/20 0.46
GABRQ Q9UN88 1/20 0.46
TSHR P16473 1/20 0.46
AOC3 Q16853 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1134458 0.89 HTR2A (0.43) CYP11B2ALOX5GABRG2GABRB3GABRA5
SCHEMBL2037015 0.89 NUDT1 (0.47) CYP11B2GABRG2GABRB3GABRA5GABRA3
SCHEMBL18080636 0.89 TSHR (0.42) CYP11B2ALOX5GABRG2GABRB3GABRA5
SCHEMBL24265435 0.89 L3MBTL1 (0.46) CYP11B2ALOX5GABRG2GABRB3GABRA5
SCHEMBL22792228 0.85 NUDT1 (0.57) CYP11B2GABRG2GABRB3GABRA5GABRA3
SCHEMBL25465500 0.85 AOC3 (0.40) CYP11B2ALOX5GABRG2GABRB3GABRA5
SCHEMBL8863973 0.85 P4HTM (0.55) P4HTM
SCHEMBL3266824 0.82 MAOB (0.47) ALOX5L3MBTL1LMNACYP1A2PTGS1
SCHEMBL2524154 0.82 L3MBTL1 (0.52) ALOX5TSHRNUDT1PKML3MBTL1
SCHEMBL2492332 0.82 KMT2A (0.47) CYP11B2GABRG2GABRB3GABRA5GABRA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed