SCHEMBL4265779

SCHEMBL4265779

CCc1ncc(OC)nc1OC

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 2/20 0.38
PDCD1 Q15116 5/20 0.36
CD274 Q9NZQ7 5/20 0.36
POLB P06746 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
RECQL P46063 1/20 0.33
PDE10A Q9Y233 5/20 0.33
ACVR2A P27037 1/20 0.33
TGFBR2 P37173 1/20 0.33
SIRT6 Q8N6T7 1/20 0.32
CCR4 P51679 1/20 0.32
APOBEC3A P31941 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6056991 0.84 POLB (0.38) PDCD1CD274POLBTDP1RECQL
SCHEMBL10271758 0.82 CCR4 (0.40) CCR4
SCHEMBL6056985 0.82 PDCD1 (0.38) PDCD1CD274POLBTDP1RECQL
SCHEMBL18517168 0.80 APOBEC3A (0.41) CRHR1PDCD1CD274PDE10ACCR4
SCHEMBL13082451 0.80 PDCD1 (0.36) CRHR1PDCD1CD274PDE10AAPOBEC3A
SCHEMBL28725927 0.79 TRPM8 (0.38) CRHR1PDCD1CD274POLBTDP1
SCHEMBL18997018 0.76 PDCD1 (0.38) CRHR1PDCD1CD274PDE10A
SCHEMBL28048106 0.73 PDCD1 (0.34) PDCD1CD274POLBTDP1RECQL
SCHEMBL4264185 0.72 RECQL (0.40) POLBTDP1RECQLPDE10ASIRT6
SCHEMBL13500438 0.71 POLB (0.36) POLBTDP1RECQLSIRT6CCR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7605215-B2 Process for producing olefin copolymerization catalyst and process for producing olefin copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-10-20 US disclosed
US-20080227937-A1 Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-09-18 US disclosed