Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.34 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.34 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.34 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1569020 | 0.91 | CCNC (0.37) | LMNAKMT2ATDP1TBXAS1KDM6B | |
| SCHEMBL4387063 | 0.91 | CCNC (0.37) | LMNAKMT2ATDP1TBXAS1KDM6B | |
| SCHEMBL4262346 | 0.91 | CCNC (0.37) | LMNAKMT2ATDP1TBXAS1KDM6B | |
| SCHEMBL1568978 | 0.89 | KDM6B (0.34) | LMNAKMT2ATDP1TBXAS1KDM6B | |
| SCHEMBL1569018 | 0.81 | BCHE (0.35) | LMNAKMT2ATDP1KDM6BALKBH2 | |
| SCHEMBL4388299 | 0.77 | CYP3A4 (0.44) | LMNAKMT2ATDP1MAPK1MEN1 | |
| SCHEMBL4390324 | 0.74 | LRRK2 (0.37) | LMNAKMT2ATDP1TBXAS1KDM6B | |
| SCHEMBL2849986 | 0.74 | ALDH1A1 (0.42) | LMNAKMT2ATDP1MAPK1MEN1 | |
| SCHEMBL4393129 | 0.72 | POLB (0.47) | LMNAKMT2ATDP1POLBBCHE | |
| SCHEMBL4393130 | 0.72 | POLB (0.47) | LMNAKMT2ATDP1POLBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143445-A1 | AZA-BETA-CARBOLINES AND METHODS OF USING SAME | THE UWM RESEARCH FOUNDATION, INC (US) | 2009-11-26 | — | — | WO | disclosed |