Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27946046 | 0.82 | MMP1 (0.35) | TSHRCYP3A4TDP1CA12CA1 | |
| SCHEMBL10561296 | 0.78 | TSHR (0.44) | TSHRGAACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27738052 | 0.77 | MMP1 (0.38) | CA12CA1CA2CA9MMP1 | |
| SCHEMBL24549619 | 0.77 | TSHR (0.43) | TSHRGAACYP3A4CA12CA1 | |
| SCHEMBL29302111 | 0.72 | ALDH1A1 (0.52) | TSHRGAAPPARDTDP1TP53 | |
| SCHEMBL14489422 | 0.72 | PPARD (0.47) | TSHRGAAPPARDTDP1TP53 | |
| SCHEMBL29194272 | 0.72 | TSHR (0.57) | TSHRCYP3A4CYP2C9CYP2C19PPARD | |
| SCHEMBL1237286 | 0.72 | TSHR (0.57) | TSHRCYP3A4CYP2C9CYP2C19PPARD | |
| SCHEMBL8954889 | 0.71 | — | — | |
| SCHEMBL280605 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2006331-B1 | POLYLACTIC ACID COMPOSITION | TEIJIN LTD (JP) | 2014-10-15 | — | — | EP | disclosed |
| EP-2006331-A9 | POLYLACTIC ACID COMPOSITION | Teijin Limited (JP) | 2009-07-29 | — | — | EP | disclosed |
| CN-101360720-A | Novel 2-aminopyrimidinone derivatives and their use | ASTRAZENECA AB (SE) | 2009-02-04 | — | — | CN | disclosed |
| EP-2006331-A2 | POLYLACTIC ACID COMPOSITION | Teijin Limited (JP) | 2008-12-24 | — | — | EP | disclosed |