SCHEMBL426709

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL431153	0.92	MAPT (1.00)	MAPTALDH1A1KMT2AKDM4ENPSR1
	SCHEMBL430625	0.90	MAPT (0.83)	MAPTALDH1A1KMT2AKDM4ENPSR1
	SCHEMBL18537710	0.89	MAPT (0.80)	MAPTALDH1A1KMT2AKDM4ENPSR1
	SCHEMBL430301	0.86	ADORA2A (0.83)	MAPTALDH1A1KMT2AKDM4ENPSR1
	SCHEMBL425245	0.86	MAPT (0.77)	MAPTALDH1A1KMT2AKDM4ENPSR1
	SCHEMBL431751	0.85	MAPT (0.75)	MAPTALDH1A1KMT2AKDM4ENPSR1
	SCHEMBL13186294	0.85	MAPT (0.77)	MAPTALDH1A1KMT2AKDM4ENPSR1
	SCHEMBL428804	0.83	MAPT (0.75)	MAPTALDH1A1KMT2AKDM4ENPSR1
	SCHEMBL424896	0.83	MAPT (0.83)	MAPTALDH1A1KMT2AKDM4ENPSR1
	SCHEMBL430493	0.82	MAPT (0.79)	MAPTALDH1A1KMT2AKDM4ENPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.