SCHEMBL4267200

SCHEMBL4267200

C1=NC(c2ccccc2)N=1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
GAA P10253 3/20 0.34
MAPT P10636 1/20 0.34
MAOB P27338 8/20 0.33
MAOA P21397 6/20 0.33
HTR2C P28335 5/20 0.33
KDM1A O60341 4/20 0.33
CYP2C19 P33261 4/20 0.33
HTR2B P41595 4/20 0.33
CYP2B6 P20813 3/20 0.33
HTR2A P28223 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
HTR1A P08908 1/20 0.33
ADRA2A P08913 1/20 0.33
CYP2A6 P11509 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16306926 0.78 P2RX7 (0.38) TSHRGAAMAPTMAOBMAOA
SCHEMBL587341 0.73
SCHEMBL4486696 0.69 TSHR (0.36) TSHRGAAMAPTMAOBMAOA
SCHEMBL12215973 0.69 TSHR (0.36) TSHRGAAMAPTMAOBMAOA
SCHEMBL12215976 0.67 GAA (0.40) TSHRGAAMAPTMAOBMAOA
SCHEMBL10513041 0.62 GAA (0.45) TSHRGAAMAPTMAOBMAOA
SCHEMBL12215971 0.62 TSHR (0.31) TSHRGAAMAOBMAOAHTR2C
SCHEMBL2031804 0.61 HDAC4 (0.46) TSHRMAOBMAOAHTR2CKDM1A
SCHEMBL31041077 0.61 HDAC4 (0.46) TSHRMAOBMAOAHTR2CKDM1A
SCHEMBL1433465 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023136361-A1 ADHESIVE COMPOSITION, ADHESIVE SHEET, ELECTROMAGNETIC-WAVE SHIELDING FILM, LAMINATE, AND PRINTED WIRING BOARD 東洋紡株式会社 2023-07-20 WO disclosed
WO-2023282318-A1 ADHESIVE COMPOSITION, ADHESIVE SHEET, ELECTROMAGNETIC-WAVE SHIELDING MATERIAL, LAMINATE, AND PRINTED WIRING BOARD 東洋紡株式会社 2023-01-12 WO disclosed
US-20090198020-A1 Polyester-Series Resin Composition and Molded Article DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2009-08-06 US disclosed
US-20090163674-A1 Polyester-Series Resin Composition and Molded Article DAICEL CHEMICAL INDUSTRIES, LTD (JP) 2009-06-25 US disclosed
EP-2011827-A1 POLYESTER RESIN COMPOSITION AND MOLDED BODY DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2009-01-07 EP disclosed
EP-1964889-A1 POLYESTER RESIN COMPOSITION AND MOLDED BODY DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2008-09-03 EP disclosed
EP-0710666-B1 Material used for immobilization of biologically active substance and method for immobilization of said substance using said material NISSHIN SPINNING (JP) 2002-04-24 EP disclosed
US-6017742-A ANTIBODIES, ANTIGENS, DNA, SYNTHETIC DNA, RNA, OR SYNTHETIC RNA REACTED WITH POLYCARBODIIMIDE POLYMER ON A CARRIER OF PLASTIC, INORGANIC POLYMER, METAL, NATURAL POLYMER, OR CERAMIC; CARRIER IS EASIER TO HANDLE NISSHINBO INDUSTRIES, INC. (JP) 2000-01-25 US disclosed
EP-0710666-A1 Material used for immobilization of biologically active substances and method for immobilization of said substance using said material NISSHINBO INDUSTRIES, INC. (JP) 1996-05-08 EP disclosed
US-5084304-A Heat resistant coating applied to a metal, a heat resistant material polymer such as a blend of a polyesterimide, a polyhydantoin, a polyamide, a polyamideimide copolymer and a polybismaleimide BASF LACKE & FARBEN AG (DE) 1992-01-28 US disclosed
US-4707512-A BLEND WITH ETHYLENE MODIFIED COPOLYMER MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) 1987-11-17 US disclosed
US-4565843-A Lacquer solutions based on hydantoin group-containing polymers BAYER AKTIENGESELLSCHAFT (DE) 1986-01-21 US disclosed
US-4465840-A REACTING CARBODIIMIDE WITH HYDROXY- OR MERCAPTO-SUCCINIC DIESTER BAYER AKTIENGESELLSCHAFT (DE) 1984-08-14 US disclosed