Phosphoric Acid

Phosphoric Acid

SCHEMBL4267407

O=C(OC(=O)C(O)CO)C(O)CO.O=P(O)(O)O

nearest known ligand 0.42

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.42
PGK1 P00558 1/20 0.37
PGK2 P07205 1/20 0.37
PGD P52209 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL93977 0.89 OR51E2 (0.50) OR51E2
SCHEMBL4985589 0.87 OR51E2 (0.48) OR51E2
Water SCHEMBL22418485 0.87 OR51E2 (0.55) OR51E2
SCHEMBL6249794 0.87 OR51E2 (0.48) OR51E2
Ethylene Glycol SCHEMBL3837465 0.84 OR51E2 (0.46) OR51E2
Ethylene SCHEMBL15065634 0.84 OR51E2 (0.46) OR51E2
1,4-Butanediol SCHEMBL11042012 0.82 OR51E2 (0.43) OR51E2
Glycerin SCHEMBL16751857 0.82 LMNA (0.47) OR51E2
Alcohol SCHEMBL6238241 0.82 OR51E2 (0.43) OR51E2
Propane SCHEMBL21814344 0.82 OR51E2 (0.43) OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090194504-A1 METHOD FOR PRODUCING ABRASIVE COMPOSITION SHOWA DENKO K.K. (JP) 2009-08-06 US disclosed
EP-2019419-A1 METHOD FOR PRODUCING POLISHING COMPOSITION Showa Denko K.K. (JP) 2009-01-28 EP disclosed
CN-100386397-C Cold feeling composition, cold feeling auxiliary composition and use thereof TAKASAGO PERFUMERY CO LTD (JP) 2008-05-07 CN disclosed
CN-1304572-C Modified antisense nucleotides complementary to section of human Ha-Ras gene HOECHST MARION & ROUSSEL DEUTS (DE) 2007-03-14 CN disclosed
CN-1922242-A Process for production of purified liquid medium-chain alkyl modified polydimethyl-siloxanes and cosmetics DOW CORNING TORAY CO LTD (JP) 2007-02-28 CN disclosed
CN-1649977-A Cold feeling composition, cold feeling auxiliary composition and use thereof TAKASAGO PERFUMERY CO LTD (JP) 2005-08-03 CN disclosed
US-20040028633-A1 Water-in-oil type emulsion composition and emulsion cosmetic made by using the same SHISEIDO COMPANY, LTD. (JP) 2004-02-12 US disclosed
EP-1336644-A1 WATER-IN-OIL EMULSION COMPOSITION AND EMULSION COSMETICS MADE BY USING THE SAME SHISEIDO COMPANY, LTD. (JP) 2003-08-20 EP disclosed
CN-1255164-A Modified antisense nucleotides complementary to human Ha-ras gene segments HOECHST MARION & ROUSSEL DEUTS (DE) 2000-05-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040028633-A1 Water-in-oil type emulsion composition and emulsion cosmetic made by using the same LIPA, LRBA, DEGS1 OR51E2 462/4885PGK1 1273/4885PGK2 1356/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.