SCHEMBL426747

SCHEMBL426747

CCCC(=O)OCC(CO)OC(CO)COC(=O)CCC

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 5/20 0.57
PRKCE Q02156 2/20 0.57
PRKCQ Q04759 2/20 0.57
PRKCD Q05655 2/20 0.57
LMNA P02545 2/20 0.49
ALDH1A1 P00352 2/20 0.49
KDM4E B2RXH2 1/20 0.47
DUSP3 P51452 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
MAPT P10636 1/20 0.43
MAPK1 P28482 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2872118 0.88 PRKCA (0.50) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL6430499 0.87 PRKCA (0.76) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL9422251 0.86 PRKCA (0.56) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL2927505 0.86 PRKCA (0.75) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL77143 0.86 PRKCA (0.75) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL237351 0.85 PRKCA (0.79) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL1924789 0.85 PRKCA (0.79) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL15011314 0.85 PRKCA (0.79) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL528141 0.85 PRKCA (0.79) PRKCAPRKCEPRKCQPRKCDLMNA
SCHEMBL4960677 0.85 PRKCA (0.54) PRKCAPRKCEPRKCQPRKCDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120020917-A1 METHODS FOR ACCELERATING WOUND HEALING BY ADMINISTRATION OF ADIPOKINES BRAIMAN-WIKSMAN LIORA (IL) 2012-01-26 US disclosed
US-20110021422-A1 METHOD AND COMPOSITIONS FOR PREVENTION AND TREATMENT OF DIABETIC AND AGED SKIN HEALOR LTD. (IL) 2011-01-27 US disclosed
US-7638484-B2 Using bioactive compounds to induce or accelerate healing of damaged skin HEALOR LTD. (IL) 2009-12-29 US disclosed