Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.58 |
| ▸ | ALPG | P10696 | 2/20 | 0.40 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL329466 | 0.98 | ALDH1A1 (0.63) | ALDH1A1POLBKMT2ATLR8ALPG | |
| Hydrochloric Acid SCHEMBL28286020 | 0.96 | ALDH1A1 (0.61) | ALDH1A1POLBKMT2ATLR8ALPG | |
| SCHEMBL4227901 | 0.92 | TLR8 (0.68) | ALDH1A1POLBKMT2ATLR8ALPG | |
| SCHEMBL28094661 | 0.91 | ALDH1A1 (0.56) | ALDH1A1POLBKMT2ATLR8ALPG | |
| SCHEMBL1879407 | 0.91 | TLR8 (0.66) | ALDH1A1POLBKMT2ATLR8ALPG | |
| SCHEMBL11531858 | 0.91 | TLR8 (0.66) | ALDH1A1POLBKMT2ATLR8ALPG | |
| SCHEMBL4230750 | 0.91 | TLR8 (0.66) | ALDH1A1POLBKMT2ATLR8ALPG | |
| SCHEMBL6889380 | 0.91 | TLR8 (0.66) | ALDH1A1POLBKMT2ATLR8ALPG | |
| SCHEMBL902006 | 0.91 | TLR8 (0.66) | ALDH1A1POLBKMT2ATLR8ALPG | |
| Bromide SCHEMBL28568345 | 0.89 | TLR8 (0.64) | ALDH1A1POLBKMT2ATLR8ALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1606845-B1 | PHOTOVOLTAIC CELLS UTILIZING MESH ELECTRODES | MERCK PATENT GMBH (DE) | 2015-10-14 | — | — | EP | disclosed |
| EP-1606845-A4 | PHOTOVOLTAIC CELLS UTILIZING MESH ELECTRODES | KONARKA TECHNOLOGIES INC (US) | 2009-05-27 | — | — | EP | disclosed |
| US-20070251570-A1 | Photovoltaic cells utilizing mesh electrodes | KONARKA TECHNOLOGIES, INC. | 2007-11-01 | — | — | US | disclosed |
| US-7022910-B2 | Photovoltaic cells utilizing mesh electrodes | KONARKA TECHNOLOGIES, INC. (US) | 2006-04-04 | — | — | US | disclosed |
| EP-1606845-A2 | PHOTOVOLTAIC CELLS UTILIZING MESH ELECTRODES | Konarka Technologies, Inc. (US) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004086464-A2 | PHOTOVOLTAIC CELLS UTILIZING MESH ELECTRODES | KONARKA TECHNOLOGIES, INC. (US) | 2004-10-07 | — | — | WO | disclosed |
| US-20030230337-A1 | Photovoltaic cells utilizing mesh electrodes | MERCK KGAA (DE) | 2003-12-18 | — | — | US | disclosed |