Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.66 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 2/20 | 0.39 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.37 |
| ▸ | GALR3 | O60755 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4230750 | 1.00 | TLR8 (0.66) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL1879407 | 1.00 | TLR8 (0.66) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL11531858 | 1.00 | TLR8 (0.66) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL6889380 | 1.00 | TLR8 (0.66) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| Hydrochloric Acid SCHEMBL29272024 | 0.98 | TLR8 (0.67) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| Bromide SCHEMBL28568345 | 0.98 | TLR8 (0.64) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| Hydrochloric Acid SCHEMBL10768898 | 0.98 | TLR8 (0.67) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL4227901 | 0.98 | TLR8 (0.68) | TLR8POLBALDH1A1KMT2ATBXAS1 | |
| SCHEMBL329466 | 0.92 | ALDH1A1 (0.63) | TLR8POLBALDH1A1KMT2AALPG | |
| Iodide SCHEMBL4267902 | 0.91 | ALDH1A1 (0.61) | TLR8POLBALDH1A1KMT2AALPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2621934-A1 | ELECTROLYTE FORMULATIONS CONTAINING CYANO-ALKOXY-BORATE ANIONS | Merck Patent GmbH (DE) | 2013-08-07 | — | — | EP | disclosed |
| WO-2012041434-A1 | ELECTROLYTE FORMULATIONS CONTAINING CYANO-ALKOXY-BORATE ANIONS | MERCK PATENT GMBH (DE) | 2012-04-05 | — | — | WO | disclosed |
| US-4140518-A | IMIDAZOLE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |
| US-4062965-A | Quaternary imidazole compounds as microbicides | TH. GOLDSCHMIDT AG (DT) | 1977-12-13 | — | — | US | disclosed |