Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.59 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4271773 | 0.98 | PTGDR2 (0.59) | PTGDR2PTGDRPPARGPPARAPPARD | |
| SCHEMBL4267950 | 0.86 | PTGDR2 (0.46) | PTGDR2ALDH1A1MAPTADRB3CYP2C9 | |
| SCHEMBL4268388 | 0.85 | PTGDR2 (0.42) | PTGDR2PPARGPPARAALDH1A1ADRB3 | |
| SCHEMBL4271751 | 0.85 | PTGDR2 (0.45) | PTGDR2PTGDRPPARGPPARA | |
| SCHEMBL4268589 | 0.85 | PTGDR2 (0.58) | PTGDR2PTGDRPPARGPPARA | |
| SCHEMBL4271611 | 0.85 | PTGDR2 (0.44) | PTGDR2PPARGPPARAPPARDALDH1A1 | |
| SCHEMBL4274009 | 0.83 | PTGDR2 (0.55) | PTGDR2PTGDR | |
| SCHEMBL4278192 | 0.83 | PTGDR2 (0.45) | PTGDR2PTGDRPPARGPPARA | |
| SCHEMBL4274214 | 0.83 | PTGDR2 (0.43) | PTGDR2PPARGPPARAPPARDALDH1A1 | |
| SCHEMBL4276034 | 0.82 | PTGDR2 (0.44) | PTGDR2PPARGPPARAADRB3CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094662-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | Astellas Pharma Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008072784-A1 | POLYCYCLIC ACID COMPOUNDS USEFUL AS CRTH2 ANTAGONISTS AND ANTIALLERGIC AGENTS | ASTELLAS PHARMA INC. (JP) | 2008-06-19 | — | — | WO | disclosed |