SCHEMBL426807

SCHEMBL426807

Cc1cc(CN2C(=O)c3c(O)c(O)c(O)c(O)c3C2=O)c(O)c(-n2nc3ccccc3n2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 7/20 0.52
RAB9A P51151 7/20 0.52
POLB P06746 2/20 0.50
LMNA P02545 1/20 0.46
ALDH1A1 P00352 5/20 0.40
SMN1; SMN2 Q16637 4/20 0.40
KDM4E B2RXH2 4/20 0.39
MAPT P10636 4/20 0.37
HPGD P15428 3/20 0.37
TDP1 Q9NUW8 2/20 0.37
TGM2 P21980 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
IGF2BP2 Q9Y6M1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30061256 1.00 NPC1 (0.52) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL30772443 0.92 NPC1 (0.53) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL29388780 0.92 NPC1 (0.53) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL674407 0.92 NPC1 (0.53) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL29353331 0.85 NPC1 (0.49) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL272931 0.85 NPC1 (0.49) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL10061927 0.83 NPC1 (0.64) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL672147 0.80 NPC1 (0.51) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL31267549 0.80 NPC1 (0.51) NPC1RAB9APOLBLMNAALDH1A1
SCHEMBL31267541 0.79 NPC1 (0.66) NPC1RAB9APOLBLMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115485347-A Adhesive sheet 日东电工株式会社 2022-12-16 CN disclosed
CN-115485348-A Adhesive sheet 日东电工株式会社 2022-12-16 CN disclosed
CN-108350260-B Thermoplastic resin composition and molded article thereof 三菱瓦斯化学株式会社 2021-01-12 CN disclosed
EP-2484658-B1 LIQUID CRYSTALLINE COMPOUND WITH NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION USING SAME, AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2017-12-06 EP disclosed
EP-2199270-B1 LIQUID CRYSTALLINE COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2016-05-25 EP disclosed
EP-2399896-B1 LIQUID CRYSTALLINE COMPOUND HAVING NEGATIVE DIELECTRIC ANISOTROPY, AND LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE EACH COMPRISING SAME JNC CORP (JP) 2016-04-13 EP disclosed
US-9109157-B2 Liquid crystal compound having negative dielectric anisotropy, liquid crystal composition and liquid crystal display device using the same JNC CORPORATION (JP) 2015-08-18 US disclosed
EP-2305627-B1 TETRACYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT JNC CORP (JP) 2014-09-17 EP disclosed
US-8673096-B2 Method of fabricating pneumatic tire TOYO TIRE & RUBBER CO., LTD. (JP) 2014-03-18 US disclosed
EP-2266941-B1 TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORP (JP) 2014-03-05 EP disclosed
EP-1860174-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE Chisso Corporation (JP) 2007-11-28 EP disclosed
US-7291368-B2 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION (JP) 2007-11-06 US disclosed
US-20070221881-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2007-09-27 US disclosed
US-20070007493-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION 2007-01-11 US disclosed
EP-1736526-A1 Liquid crystal composition and liquid crystal display device CHISSO CORPORATION (JP) 2006-12-27 EP disclosed
US-20060210725-A1 Liquid crystal composition and liquid crystal display device JNC PETROCHEMICAL CORPORATION (JP) 2006-09-21 US disclosed
US-20050230661-A1 Liquid crystal composition and liquid crystal display element CHISSO CORPORATION 2005-10-20 US disclosed
US-20050224758-A1 Liquid crystal composition and liquid crystal display device JIANGSU HECHENG DISPLAY TECHNOLOGY CO., LTD. (CN) 2005-10-13 US disclosed
US-6921560-B2 Liquid crystal composition and liquid crystal display element CHISSO PETROCHEMICAL CORPORATION (JP) 2005-07-26 US disclosed
US-20040155223-A1 Liquid crystal composition and liquid crystal display element JNC PETROCHEMICAL CORPORATION (JP) 2004-08-12 US disclosed