Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5167233 | 1.00 | TDP1 (0.34) | TDP1AKR1B1TSHR | |
| SCHEMBL7681610 | 0.88 | TDP1 (0.33) | TDP1AKR1B1TSHR | |
| SCHEMBL27671086 | 0.85 | TSHR (0.36) | TDP1AKR1B1TSHR | |
| SCHEMBL755228 | 0.84 | TSHR (0.42) | TDP1TSHR | |
| Acetic Acid SCHEMBL10782395 | 0.84 | LMNA (0.31) | — | |
| SCHEMBL28554669 | 0.83 | TDP1 (0.47) | TDP1 | |
| SCHEMBL669311 | 0.83 | TDP1 (0.47) | TDP1 | |
| SCHEMBL3489131 | 0.83 | TDP1 (0.47) | TDP1 | |
| SCHEMBL845645 | 0.83 | TDP1 (0.47) | TDP1 | |
| SCHEMBL23121474 | 0.82 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8084016-B2 | Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolitic products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-27 | — | — | US | disclosed |
| US-20090041661-A1 | MEASUREMENT OF BIOSYNTHESIS AND BREAKDOWN RATES OF BIOLOGICAL MOLECULES THAT ARE INACCESSIBLE OR NOT EASILY ACCESSIBLE TO DIRECT SAMPLING, NON-INVASIVELY, BY LABEL INCORPORATION INTO METABOLIC DERIVATIVES AND CATABOLITIC PRODUCTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-02-12 | — | — | US | disclosed |
| US-7449171-B2 | Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolic products | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-11-11 | — | — | US | disclosed |
| EP-1483399-B1 | MEASUREMENT OF BIOSYNTHESIS AND BREAKDOWN RATES OF BIOLOGICAL MOLECULES THAT ARE INACCESSIBLE OR NOT EASILY ACCESSIBLE TO DIRECT SAMPLING, NON-INVASIVELY, BY LABEL INCORPORATION INTO METABOLIC DERIVATIVES AND CATABOLITIC PRODUCTS | UNIV CALIFORNIA (US) | 2008-10-29 | — | — | EP | disclosed |
| EP-1483399-A4 | MEASUREMENT OF BIOSYNTHESIS AND BREAKDOWN RATES OF BIOLOGICAL MOLECULES THAT ARE INACCESSIBLE OR NOT EASILY ACCESSIBLE TO DIRECT SAMPLING, NON-INVASIVELY, BY LABEL INCORPORATION INTO METABOLIC DERIVATIVES AND CATABOLITIC PRODUCTS | UNIV CALIFORNIA (US) | 2006-07-19 | — | — | EP | disclosed |
| EP-1483399-A2 | MEASUREMENT OF BIOSYNTHESIS AND BREAKDOWN RATES OF BIOLOGICAL MOLECULES THAT ARE INACCESSIBLE OR NOT EASILY ACCESSIBLE TO DIRECT SAMPLING, NON-INVASIVELY, BY LABEL INCORPORATION INTO METABOLIC DERIVATIVES AND CATABOLITIC PRODUCTS | The Regents of the University of California (US) | 2004-12-08 | — | — | EP | disclosed |
| US-20030228259-A1 | Measurement of biosynthesis and breakdown rates of biological molecules that are inaccessible or not easily accessible to direct sampling, non-invasively, by label incorporation into metabolic derivatives and catabolitic products | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2003-12-11 | — | — | US | disclosed |
| WO-2003068919-A2 | NON-INVASIVE METHOD FOR MEASURING RATES OF BIOSYNTHESIS OF BIOLOGICAL MOLECULES BY LABEL INCORPORATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-08-21 | — | — | WO | disclosed |