Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL10786614 | 0.94 | LMNA (0.39) | TDP1LMNAPDE4A | |
| SCHEMBL9468059 | 0.90 | TDP1 (0.32) | TDP1LMNAPDE4AL3MBTL1USP2 | |
| Acetic Acid SCHEMBL10783619 | 0.90 | LMNA (0.36) | LMNA | |
| SCHEMBL4606281 | 0.89 | — | — | |
| SCHEMBL4606284 | 0.89 | — | — | |
| SCHEMBL11692478 | 0.89 | PDE4A (0.31) | LMNAPDE4AL3MBTL1 | |
| SCHEMBL4651155 | 0.88 | — | — | |
| SCHEMBL5167233 | 0.88 | TDP1 (0.34) | TDP1AKR1B1TSHR | |
| SCHEMBL4268170 | 0.88 | TDP1 (0.34) | TDP1AKR1B1TSHR | |
| SCHEMBL7068618 | 0.87 | LMNA (0.37) | TDP1LMNAPDE4AL3MBTL1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380168-B1 | ADMINISTERING 3-O-.BETA.-GLUCOPYRANOSYL(1-6)-.BETA.-D-GLUCOPYRANOSYL INDOLE, 2-S-.BETA.-D-GLUCOPYRANOSYL-3-O-.BETA.-D-GLUCOPYRANOSYL-2-MERC APTOINDOLE FOR INCREASING BLOOD FLOW TO SKIN | NOMURA CO., LTD. (JP) | 2002-04-30 | — | — | US | disclosed |
| US-6297363-B1 | 3-O-BETA-D-GLUCOPYRANOSYL(1-6)-BETA-D-GLUCOPYRANOSYL INDOLE; ISOLATED FROM CALANTHE DISCOLOR LINDL; FOR PROMOTION OF HAIR GROWTH AND RESTORATION | NOMURA CO., LTD. (JP) | 2001-10-02 | — | — | US | disclosed |