SCHEMBL9974560

SCHEMBL9974560

O=C(O)CN(CC(=O)O)CC(=O)Nc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA1 P00915 13/20 0.64
CA2 P00918 13/20 0.64
ALOX15 P16050 1/20 0.58
TSHR P16473 1/20 0.58
CYP2C19 P33261 1/20 0.58
HIF1A Q16665 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
CA12 O43570 4/20 0.56
CA9 Q16790 4/20 0.56
CA4 P22748 4/20 0.55
HDAC1 Q13547 1/20 0.55
EPHX2 P34913 1/20 0.53
L3MBTL1 Q9Y468 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9639810 0.94 HDAC1 (0.59) CA1CA2TSHRHDAC1EPHX2
SCHEMBL4268752 0.91 CA1 (0.67) CA1CA2ALOX15TSHRCYP2C19
SCHEMBL4272357 0.91 CA1 (0.67) CA1CA2ALOX15TSHRCYP2C19
SCHEMBL4365925 0.86 HDAC1 (0.65) CA1CA2TSHRCA12CA9
SCHEMBL17883376 0.84 CA1 (0.53) CA1CA2ALOX15TSHRCYP2C19
SCHEMBL9515833 0.84 CA2 (0.63) CA1CA2ALOX15TSHRCYP2C19
SCHEMBL9514501 0.84 CA1 (0.68) CA1CA2ALOX15TSHRCYP2C19
SCHEMBL9617679 0.84 BCHE (0.62) CA1CA2ALOX15TSHRCYP2C19
SCHEMBL15499792 0.83 CA1 (0.75) CA1CA2ALOX15TSHRCYP2C19
SCHEMBL8623174 0.83 ALDH1A1 (0.68) HDAC1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0133603-A1 Specific relaxation agents for organs or pathologics for use in modifying the contrast of medical imagery by nuclear magnetic resonance Société anonyme: COMPAGNIE ORIS INDUSTRIE (FR) 1985-02-27 EP claimed
US-9040129-B2 Protective film of polarizer, polarizer and method for producing it, and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-05-26 US disclosed
US-20150055062-A1 OPTICAL FILM, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-02-26 US disclosed
US-8394309-B2 Resin film and method for producing it, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2013-03-12 US disclosed
US-8337962-B2 Resin film and method for producing it, polarizer and liquid crystal display device FUJIFILM CORPORATION (JP) 2012-12-25 US disclosed
US-20120153542-A1 RESIN FILM AND METHOD FOR PRODUCING IT, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-06-21 US disclosed
US-20110273646-A1 Protective film of polarizer, polarizer and method for producing it, and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-11-10 US disclosed
US-20110223435-A1 RESIN FILM AND METHOD FOR PRODUCING IT, POLARIZER AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-09-15 US disclosed
US-4804529-A Use of specific relaxation agents for organs or pathologies for modifying the contrasts in medical imaging by nuclear magnetic resonance COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1989-02-14 US disclosed
EP-0133603-A1 Specific relaxation agents for organs or pathologics for use in modifying the contrast of medical imagery by nuclear magnetic resonance Société anonyme: COMPAGNIE ORIS INDUSTRIE (FR) 1985-02-27 EP disclosed