Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL612241 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KEAP1KDM4ETDP1 | |
| SCHEMBL2762716 | 0.80 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1KEAP1KDM4ETDP1 | |
| SCHEMBL5394557 | 0.76 | GLA (0.44) | SMN1; SMN2ALDH1A1KDM4ETDP1GLA | |
| SCHEMBL10613341 | 0.76 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1KEAP1KDM4ETDP1 | |
| SCHEMBL29030826 | 0.75 | POLB (0.41) | SMN1; SMN2SIGMAR1CYP1A2CHRM2KCNH2 | |
| SCHEMBL27923962 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2ALDH1A1KEAP1KDM4ETDP1 | |
| SCHEMBL235080 | 0.74 | KDM4E (0.65) | SMN1; SMN2ALDH1A1KEAP1KDM4ESIGMAR1 | |
| SCHEMBL81823 | 0.71 | TDP1 (0.56) | SMN1; SMN2ALDH1A1KEAP1KDM4ETDP1 | |
| SCHEMBL10913328 | 0.71 | KDM4E (0.70) | SMN1; SMN2ALDH1A1KEAP1KDM4ESIGMAR1 | |
| SCHEMBL11856358 | 0.71 | KDM4E (0.70) | SMN1; SMN2ALDH1A1KEAP1KDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8197591-B2 | Pearlescent pigments having a secondary coating comprising α-silanes and method for the production thereof | ECKART GMBH (DE) | 2012-06-12 | — | — | US | disclosed |
| US-20090249979-A1 | PEARLESCENT PIGMENTS HAVING A SECONDARY COATING COMPRISING ALPHA-SILANES AND METHOD FOR THE PRODUCTION THEREOF | ECKART GMBH (DE) | 2009-10-08 | — | — | US | disclosed |
| US-7276615-B2 | Organofunctional surface-modified metal oxides | WACKER CHEMIE AG (DE) | 2007-10-02 | — | — | US | disclosed |
| US-20040220419-A1 | Organofunctional surface-modified metal oxides | WACKER-CHEMIE GMBH (DE) | 2004-11-04 | — | — | US | disclosed |