SCHEMBL4269019

SCHEMBL4269019

Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 17/20 1.00
ABL1 P00519 9/20 1.00
YES1 P07947 7/20 1.00
PDGFRB P09619 7/20 1.00
KDR P35968 5/20 1.00
EPHB4 P54760 5/20 1.00
LCK P06239 4/20 1.00
RET P07949 3/20 1.00
GAK O14976 2/20 1.00
RIPK2 O43353 2/20 1.00
BCR P11274 2/20 1.00
EPHA2 P29317 2/20 1.00
EPHB2 P29323 2/20 1.00
ABL2 P42684 2/20 1.00
EPHA4 P54764 2/20 1.00
DDR1 Q08345 2/20 1.00
CIT O14578 1/20 1.00
EPHB6 O15197 1/20 1.00
PRKD3 O94806 1/20 1.00
BRAF P15056 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29366448 1.00 SRC (1.00) SRCABL1YES1PDGFRBKDR
Hydrochloric Acid SCHEMBL4268361 0.99 SRC (0.98) SRCABL1YES1PDGFRBKDR
SCHEMBL15095269 0.92 SRC (0.86) SRCABL1YES1PDGFRBKDR
SCHEMBL4272173 0.91 SRC (1.00) SRCABL1YES1PDGFRBKDR
SCHEMBL4265021 0.91 SRC (1.00) SRCABL1YES1PDGFRBKDR
SCHEMBL4275780 0.89 SRC (1.00) SRCABL1YES1PDGFRBKDR
SCHEMBL4272203 0.89 SRC (1.00) SRCABL1YES1PDGFRBKDR
SCHEMBL4264210 0.89 SRC (0.85) SRCABL1YES1PDGFRBKDR
SCHEMBL12198200 0.88 SRC (0.80) SRCABL1YES1PDGFRBKDR
SCHEMBL231130 0.88 SRC (0.78) SRCABL1YES1PDGFRBKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954436-B1 METHOD FOR PRODUCING BIOTISSUE-LIKE STRUCTURE ORIZURU THERAPEUTICS INC (JP) 2026-01-07 EP disclosed
US-12268715-B2 Method for producing biological tissue-like structure Orizuru Therapeutics, Inc. (JP) 2025-04-08 US disclosed
CN-112867787-B Insulin producing cells 千纸鹤治疗公司 2024-11-22 CN disclosed
US-20240318141-A1 MATURATION AGENT Orizuru Therapeutics, Inc. (JP) 2024-09-26 US disclosed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO disclosed
CN-112313327-B Proliferation inhibitors 千纸鹤治疗公司 2024-04-19 CN disclosed
EP-3700516-B1 INHIBITORS OF DUX4 INDUCTION FOR REGULATION OF MUSCLE FUNCTION SONIC MASTER LTD (VG) 2024-01-24 EP disclosed
EP-4293105-A1 MATURATION AGENT Orizuru Therapeutics, Inc. (JP) 2023-12-20 EP disclosed
WO-2023130150-A2 SYSTEMS, CELL LINES AND METHODS OF PRODUCING AND USING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-07-06 WO disclosed
WO-2022172960-A1 MATURATION AGENT オリヅルセラピューティクス株式会社 2022-08-18 WO disclosed
US-20110294796-A1 BENZOTRIAZINE INHIBITORS OF KINASES TARGEGEN, INC. (US) 2011-12-01 US disclosed
US-20110243999-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS TARGEGEN INC. 2011-10-06 US disclosed
US-20110243999-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS TARGEGEN INC. 2011-10-06 US disclosed
US-20090275569-A1 Benzotriazine Inhibitors of Kinases TARGEGEN, INC. 2009-11-05 US disclosed
US-20090275569-A1 Benzotriazine Inhibitors of Kinases TARGEGEN, INC. 2009-11-05 US disclosed
US-20090275569-A1 Benzotriazine Inhibitors of Kinases TARGEGEN, INC. 2009-11-05 US disclosed
US-7456176-B2 Benzotriazine inhibitors of kinases TARGEGEN, INC. (US) 2008-11-25 US disclosed
US-7456176-B2 Benzotriazine inhibitors of kinases TARGEGEN, INC. (US) 2008-11-25 US disclosed
US-7456176-B2 Benzotriazine inhibitors of kinases TARGEGEN, INC. (US) 2008-11-25 US disclosed
US-20050245524-A1 Benzotriazine inhibitors of kinases TARGEGEN, INC. (US) 2005-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294796-A1 BENZOTRIAZINE INHIBITORS OF KINASES SRC, CAMK4, CAMK2G SRC 1/4885ABL1 15/4885YES1 237/4885
US-20090275569-A1 Benzotriazine Inhibitors of Kinases SRC, CAMK4, CAMK2G SRC 1/4885ABL1 15/4885YES1 237/4885
US-20050245524-A1 Benzotriazine inhibitors of kinases SRC, CAMK4, CAMK2G SRC 1/4885ABL1 15/4885YES1 237/4885
US-20110243999-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF OCULAR DISORDERS AQP3, AQP1, AQP4 SRC 4062/4885ABL1 4620/4885YES1 3099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.