SCHEMBL426922

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL427097	0.93	KIT (0.44)	ALOX15MEN1KMT2AALDH1A1KDM4E
	SCHEMBL426562	0.89	ALDH1A1 (0.50)	ALOX15MEN1KMT2AALDH1A1HPGD
	SCHEMBL427273	0.89	CSF1R (0.46)	ALOX15MEN1KMT2AALDH1A1KDM4E
	SCHEMBL429214	0.87	ALDH1A1 (0.45)	ALOX15MEN1KMT2AALDH1A1KDM4E
	SCHEMBL429174	0.85	ALDH1A1 (0.49)	ALOX15MEN1KMT2AALDH1A1HPGD
	SCHEMBL4133628	0.84	ALDH1A1 (0.48)	ALOX15MEN1KMT2AALDH1A1HPGD
	SCHEMBL14412940	0.84	KIT (0.41)	ALOX15MEN1KMT2AALDH1A1KDM4E
	SCHEMBL429389	0.83	ALDH1A1 (0.48)	ALOX15MEN1KMT2AALDH1A1HPGD
	SCHEMBL426608	0.83	ALDH1A1 (0.49)	ALOX15MEN1KMT2AALDH1A1KDM4E
	SCHEMBL425631	0.83	ALDH1A1 (0.51)	ALOX15MEN1KMT2AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.