Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.54 |
| ▸ | HTR3B | O95264 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1365883 | 0.91 | LMNA (0.47) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL5540272 | 0.86 | LMNA (0.50) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL4671620 | 0.82 | LTA4H (0.64) | LMNAMAPTHSD17B10SMN1; SMN2MEN1 | |
| SCHEMBL385012 | 0.81 | — | — | |
| SCHEMBL576814 | 0.81 | LMNA (0.67) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL164538 | 0.81 | LMNA (0.67) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL576454 | 0.81 | LMNA (0.67) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL16924853 | 0.81 | LMNA (0.67) | LMNASIGMAR1HTR3EHTR3BADRB1 | |
| SCHEMBL5538364 | 0.80 | CHKA (0.45) | LMNAMAPTCYP3A4ALOX15MAPK1 | |
| SCHEMBL4671113 | 0.79 | SLC6A2 (0.49) | ADRB1MAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2617 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12020872-B2 | Stilbene and fused stilbene derivatives as solar cell dyes | Ambient Photonics, Inc. (US) | 2024-06-25 | — | — | US | claimed |
| CN-115108931-B | Tofenamic acid derivative and preparation and application thereof | 南华大学附属第一医院 | 2024-06-14 | — | — | CN | claimed |
| CN-117986271-A | Cell cycle regulator, and pharmaceutical preparation and application thereof | 贵州大学 | 2024-05-07 | — | — | CN | claimed |
| CN-110770214-B | Heterocyclic P2X7 antagonists | 布雷耶疗法有限公司 | 2024-03-29 | — | — | CN | claimed |
| US-11664171-B2 | Stilbene and fused stilbene derivatives as solar cell dyes | Ambient Photonics, Inc. (US) | 2023-05-30 | — | — | US | claimed |
| US-20230154691-A1 | Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes | Ambient Photonics, Inc. (US) | 2023-05-18 | — | — | US | claimed |
| US-20230133132-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. | 2023-05-04 | — | — | US | claimed |
| US-11623919-B2 | Heterocyclic P2X7 antagonists | BREYE THERAPEUTICS APS (DK) | 2023-04-11 | — | — | US | claimed |
| WO-2023051261-A1 | IMINE COMPOUND AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2023-04-06 | — | — | WO | claimed |
| CN-115872901-A | Imine compound and application thereof | 沈阳中化农药化工研发有限公司 | 2023-03-31 | — | — | CN | claimed |
| EP-0005745-A1 | Pyrazolo (3,4-c) and thiazolo (5,4-c) isoquinolines, methods for preparing them, these compounds for use as antiinflammatory, CNS-depressant and anti-anxiety agents and pharmaceutical compositions thereof | GRUPPO LEPETIT S.P.A. (IT) | 1979-12-12 | — | — | EP | claimed |
| US-4061637-A | CNS, CARDIOVASCULAR, ANTIINFLAMMATORY, ADRENOLYTIC, ANTIULCER | ISTITUTO LUSO FARMACO D'ITALIA S.R.L. (IT) | 1977-12-06 | — | — | US | claimed |
| US-4022779-A | DEPRESSANT, ANTI-FLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-4022782-A | ANTI-INFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-05-10 | — | — | US | claimed |
| US-4018782-A | 1-OXAPENICILLINS, ANTIBIOTICS | QUEEN'S UNIVERSITY (CA) | 1977-04-19 | — | — | US | claimed |
| US-4006232-A | Therapeutic method of treating cardiac arrhythmias utilizing 3-substituted diphenylhydantoins | MILES LABORATORIES, INC. (US) | 1977-02-01 | — | — | US | claimed |
| US-3994890-A | TRANQUILIZERS, ANTIDEPRESSANTS, ANTIINFLAMMATORY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-11-30 | — | — | US | claimed |
| US-3984562-A | TREATING ANXIETY | AMERICAN CYANAMID COMPANY (US) | 1976-10-05 | — | — | US | claimed |
| US-3979391-A | 1,2,3,4-Tetrahydrocarbazoles | STERLING DRUG INC. (US) | 1976-09-07 | — | — | US | claimed |
| US-3960886-A | Substituted N-arylanilines | STERLING DRUG INC. (US) | 1976-06-01 | — | — | US | claimed |