SCHEMBL4270977

SCHEMBL4270977

C=C(C)C(=O)OCCC[Si](OC(=O)C(F)(F)F)(OC(=O)C(F)(F)F)OC(=O)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
THRB P10828 1/20 0.40
POLB P06746 1/20 0.37
APEX1 P27695 1/20 0.37
HTT P42858 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31278365 0.85 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4272606 0.85 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL483520 0.82 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL143449 0.82 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL28347798 0.81 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL7737927 0.80 TSHR (0.59) TSHRTHRBPOLBAPEX1HTT
SCHEMBL10793142 0.79 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL4270975 0.79 CES2 (0.38)
SCHEMBL2779311 0.78 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL15276 0.77 TSHR (0.55) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998691-A Antireflection film, liquid composition set, and method for producing antireflection film 日本板硝子株式会社 2025-05-13 CN disclosed
US-7604866-B2 Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance ASAHI KASEI KABUSHIKI KAISHA (JP) 2009-10-20 US disclosed
US-20060269724-A1 Comprising silica particles and at least one binder compound; good mechanical strength and abrasion resistance ASAHI KASEI KABUSHIKI KAISHA (JP) 2006-11-30 US disclosed