SCHEMBL143449

SCHEMBL143449

C=C(C)C(=O)OCCC[Si](OC(C)=O)(OC(C)=O)OC(C)=O

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.53
THRB P10828 1/20 0.46
POLB P06746 1/20 0.41
APEX1 P27695 1/20 0.41
HTT P42858 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28347798 0.98 TSHR (0.51) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2779311 0.95 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL20787785 0.93 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL31278365 0.93 TSHR (0.56) TSHRTHRBPOLBAPEX1HTT
SCHEMBL7909983 0.92 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL7635661 0.92 TSHR (0.49) TSHRTHRBPOLBAPEX1HTT
SCHEMBL483520 0.89 TSHR (0.53) TSHRTHRBPOLBAPEX1HTT
SCHEMBL2779024 0.89 THRB (0.48) TSHRTHRBPOLBAPEX1HTT
SCHEMBL7641347 0.89 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT
SCHEMBL7641421 0.89 TSHR (0.50) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 832 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059985-A Methacryloxypropyl triacetyl preparation method of oxo silane 山东硅科新材料有限公司 2026-05-19 CN claimed
EP-4628551-A1 COATING MATERIAL FOR STEEL SHEET, AND STEEL SHEET HAVING ELECTRON-BEAM-CURED COATING LAYER FORMED THEREFROM BAOSHAN IRON & STEEL CO., LTD. (CN) 2025-10-08 EP claimed
US-12358933-B2 Meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method PIOCEL CO., LTD. (KR) 2025-07-15 US claimed
US-20250109153-A1 A novel meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method PIOCEL CO., LTD. (KR) 2025-04-03 US claimed
EP-3307816-B1 HIGH STRENGTH AND MOISTURE RESISTANT ADHESIVE BISON INT B V (NL) 2025-02-26 EP claimed
CN-119285984-A Modified cyclodextrin metal frame material, paintable dealcoholized silicone sealant and preparation method thereof 广州白云科技股份有限公司 2025-01-10 CN claimed
US-12084591-B2 Three-dimensional articles made by additive manufacturing having reduced surface haze HENKEL AG & CO. KGAA (DE) 2024-09-10 US claimed
WO-2024168360-A2 ENHANCED EMISSIVITY OF POLYMER COMPOSITIONS FOR RADIATIVE COOLING APPLICATIONS FUTUREWEI TECHNOLOGIES, INC. (US) 2024-08-15 WO claimed
CN-117487081-A Environment-friendly polymer composite multielement copolymerization filtrate reducer and preparation method thereof 四川盛年同缔实业有限公司 2024-02-02 CN claimed
CN-114315890-B Preparation method of methacryloxypropyl triacetoxy silane 湖北江瀚新材料股份有限公司 2023-11-17 CN claimed
US-20100323073-A1 FRESHWATER DIATOMACEOUS EARTH PRODUCTS CONTAINING REDUCED SOLUBLE METAL LEVELS, PROCESSES FOR REDUCING SOLUBLE METAL LEVELS IN FRESHWATER DIATOMACEOUS EARTH PRODUCTS, AND METHODS OF USING THE SAME IMERYS FILTRATION MINERALS, INC. 2010-12-23 US claimed
WO-2010130241-A2 PHENOLATE ESTER COMPOUNDS NANO-X GMBH (DE) 2010-11-18 WO claimed
WO-2009127438-A1 SURFACE MODIFIED SILICON DIOXIDE PARTICLES NANORESINS AG 2009-10-22 WO claimed
EP-1992230-A2 Antibacterial agent NANO-X GmbH (DE) 2008-11-19 EP claimed
EP-0841383-B1 Alkoxysilyl-functional oligomers in curable silane polymer compositions CROMPTON CORP (US) 2003-04-02 EP claimed
US-6177534-B1 ADHESIVE BINDER FOR COMPOSITES AND IN SEALANT AND ADHESIVE DENTAL APPLICATIONS THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF COMMERCE 2001-01-23 US claimed
US-5338877-A Fluoroalkyl group-containing organosilicon oligomer, method for preparing same and surface treating agent NIPPON OIL AND FATS CO., LTD. (JP) 1994-08-16 US claimed
EP-0124247-B1 MODIFIED POLYOLEFIN COMPOSITION USEFUL FOR BONDING MATERIALS UBE INDUSTRIES, LTD. (JP) 1990-08-29 EP claimed
US-4642260-A Substrate for planographic plate UBE INDUSTRIES, LTD. (JP) 1987-02-10 US claimed
US-4533602-A PROPYLENE AND ETHYLENE HOMOPOLYMERS AND COPOLYMERS AND ORGANO SILAANE MODIFIED POLYMERS UBE INDUSTRIES, LTD. (JP) 1985-08-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12358933-B2 Meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method SPEN, SAE1, OSTC TSHR 3556/4885THRB 3131/4885POLB 925/4885
US-20250109153-A1 A novel meta-POSS (meta-polyhedral oligomeric silsesquioxane) compound, a preparation method thereof, and a composition containing the meta-POSS compound prepared by the preparation method SPEN, SAE1, SOST TSHR 3789/4885THRB 3126/4885POLB 830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.