Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.55 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.52 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18528838 | 0.89 | TDP1 (0.64) | TDP1TSHRMAPTPTGDR2PTGDR | |
| Metaxon SCHEMBL28681554 | 0.82 | TDP1 (0.62) | TDP1TSHRMAPTPTGDR2SMN1; SMN2 | |
| SCHEMBL48123 | 0.80 | TSHR (0.46) | TDP1TSHRPTGDR2PTGDRSMN1; SMN2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL29010269 | 0.79 | TDP1 (0.82) | TDP1TSHRMAPTPTGDR2SMN1; SMN2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL437562 | 0.79 | TDP1 (0.82) | TDP1TSHRMAPTPTGDR2SMN1; SMN2 | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL29010254 | 0.79 | TDP1 (0.82) | TDP1TSHRMAPTPTGDR2SMN1; SMN2 | |
| SCHEMBL5389347 | 0.79 | TDP1 (0.77) | TDP1TSHRMAPTPTGDR2PTGDR | |
| Metaxon SCHEMBL16041675 | 0.78 | TDP1 (0.60) | TDP1TSHRMAPTPTGDR2SMN1; SMN2 | |
| SCHEMBL3729663 | 0.78 | TDP1 (0.60) | TDP1TSHRMAPTPTGDR2PTGDR | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL23242752 | 0.78 | TDP1 (0.93) | TDP1TSHRMAPTPTGDR2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524715-B2 | Phenoxyacetic acid derivatives useful for treating respiratory diseases | ASTRAZENECA AB (SE) | 2013-09-03 | — | — | US | disclosed |
| US-20090149448-A1 | Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases | ASTRAZENECA AB (SE) | 2009-06-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149448-A1 | Phenoxyacetic Acid Derivatives Useful for Treating Respiratory Diseases | PAOX, PCCA, PAH | TDP1 4144/4885TSHR 1896/4885MAPT 1955/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.