Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.54 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.51 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.50 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5389347 | 0.87 | TDP1 (0.77) | TDP1TSHRMAPTPTGDR2PTGDR | |
| SCHEMBL1332214 | 0.81 | TDP1 (0.68) | TDP1TSHRMAPTPTGDR2PTGDR | |
| SCHEMBL3738383 | 0.79 | LMNA (0.50) | TDP1MAPTPTGER1SMN1; SMN2 | |
| SCHEMBL18528838 | 0.79 | TDP1 (0.64) | TDP1TSHRMAPTPTGDR2PTGDR | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL910271 | 0.79 | TDP1 (0.68) | TDP1TSHRMAPTPTGDR2PTGDR | |
| SCHEMBL13347438 | 0.78 | KDM1A (0.54) | TDP1MAPTPTGER1SMN1; SMN2 | |
| SCHEMBL4626761 | 0.78 | MAPT (0.58) | TDP1TSHRMAPTPTGDR2PTGDR | |
| 2,4-Dichlorophenoxyacetic Acid SCHEMBL29010254 | 0.78 | TDP1 (0.82) | TDP1TSHRMAPTPTGDR2SMN1; SMN2 | |
| SCHEMBL4271125 | 0.78 | TDP1 (0.62) | TDP1TSHRMAPTPTGDR2PTGDR | |
| Metaxon SCHEMBL28681554 | 0.78 | TDP1 (0.62) | TDP1TSHRMAPTPTGDR2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | BOUILLOT ANNE MARIE JEANNE | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120669-A1 | THIADIAZOLE DERIVATIVES, INHIBITORS OF STEAROYL-COA DESATURASE | SCD, SCD5, FADS2 | TDP1 1661/4885TSHR 2858/4885MAPT 2890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.