SCHEMBL4271328

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4279613	0.93	PDE4B (0.48)	PDE4APDE4BPDE4CPDE4DMEN1
	SCHEMBL20053165	0.92	PDE4A (0.44)	PDE4APDE4BPDE4CPDE4DMEN1
	SCHEMBL4271668	0.91	PDE4A (0.44)	PDE4APDE4BPDE4CPDE4DMEN1
	SCHEMBL4269941	0.91	PTGS2 (0.46)	PTGS2PDE4APDE4BPDE4CPDE4D
	SCHEMBL4280362	0.90	PDE4B (0.45)	PDE4APDE4BPDE4CPDE4DHPGD
	SCHEMBL4285834	0.90	PDE4B (0.43)	PDE4APDE4BPDE4CPDE4DHPGD
	SCHEMBL4279381	0.89	KMT2A (0.43)	PDE4APDE4BPDE4CPDE4DMEN1
	SCHEMBL4639291	0.89	PDE4B (0.47)	PDE4APDE4BPDE4CPDE4DMEN1
	SCHEMBL4278563	0.89	PDE4A (0.45)	PDE4APDE4BPDE4CPDE4DMAPT
	SCHEMBL4278639	0.89	PDE4B (0.48)	PDE4APDE4BPDE4CPDE4DMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.