Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4272738 | 0.81 | CDK1 (0.51) | HDAC6HSP90AA1HSP90AB1 | |
| SCHEMBL2904804 | 0.76 | KDM4E (0.38) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL4267091 | 0.75 | ADORA2A (0.50) | ALDH1A1 | |
| SCHEMBL14138147 | 0.71 | HDAC6 (0.46) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL14642669 | 0.69 | CDK1 (0.56) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL3291370 | 0.69 | HDAC6 (0.39) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL2914357 | 0.68 | KDM4E (0.46) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL2914353 | 0.68 | KDM4E (0.46) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL4961034 | 0.67 | HDAC6 (0.45) | HDAC6KDM4EALDH1A1HPGDADRA1A | |
| SCHEMBL28749029 | 0.66 | KDM4E (0.44) | HDAC6KDM4EALDH1A1HPGDADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7605147-B2 | Acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | LG LIFE SCIENCES LTD. (KR) | 2009-10-20 | — | — | US | claimed |
| US-20060293284-A1 | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | CHO DONG-GYU | 2006-12-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060293284-A1 | Novel acyclic nucleoside phosphonate derivatives, salts thereof and process for the preparation of the same | PNP, ITPA, MTAP | HDAC6 1806/4885KDM4E 4056/4885ALDH1A1 2937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.