SCHEMBL4273168

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4271695	0.94	GSK3B (0.45)	LMNAGSK3BCDK2SMN1; SMN2PKM
	SCHEMBL4275012	0.91	GSK3B (0.41)	LMNAGSK3BCDK2KLKB1PKM
	SCHEMBL4282848	0.90	GSK3B (0.41)	LMNAGSK3BCDK2KLKB1PKM
	SCHEMBL4276879	0.90	HSD17B10 (0.44)	LMNAGSK3BCDK2SMN1; SMN2KLKB1
	SCHEMBL4286005	0.90	S1PR1 (0.39)	LMNAGSK3BCDK2S1PR1KLKB1
	SCHEMBL4280816	0.90	GSK3B (0.41)	GSK3BCDK2KLKB1PKMHPGD
	SCHEMBL4278398	0.90	GSK3B (0.41)	LMNAGSK3BCDK2SMN1; SMN2KLKB1
	SCHEMBL4276096	0.90	GSK3B (0.42)	LMNAGSK3BCDK2SMN1; SMN2S1PR1
	SCHEMBL4270616	0.89	GSK3B (0.44)	GSK3BCDK2KLKB1PKMHPGD
	SCHEMBL4285870	0.89	PDE4A (0.43)	GSK3BCDK2KLKB1PKMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.